Evidence map›Paper›PMID 40193000›Full record

ArticleBiological trace element research2025

Boron Prevents Oral Acrylamide Damage in Bone Marrow and Hematologic Parameters of Wistar Rats.

Faysal Selimoğlu, Mustafa Cengiz, Canan Vejselova Sezer, Adnan Ayhanci, Fatma Gür, Özge Yıldırım, Bahri Gür, Ahmet Musmul

Abstract read
In one paragraph

Article in Biological trace element research, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Faysal SelimoğluDepartment of Biotechnology, Faculty of Science, Necmettin Erbakan University, Konya, Türkiye.
Mustafa CengizDepartment of Elementary Education, Faculty of Education, Siirt University, Siirt, Türkiye. m.cengiz@siirt.edu.tr.
Canan Vejselova SezerDepartment of Biology, Faculty of Science and Arts, Kütahya Dumlupınar University, Kütahya, Türkiye.
Adnan AyhanciDepartment of Biology, Faculty of Science, Eskişehir Osmangazi University, Eskişehir, Türkiye.
Fatma GürDepartment of Dentistry Services, Atatürk University, Erzurum, Türkiye.
Özge YıldırımDepartment of Biology, Faculty of Science, Eskişehir Osmangazi University, Eskişehir, Türkiye.
Bahri GürDepartment of Biochemistry, Faculty of Science, Iğdır University, Iğdır, Türkiye. bahri.gur@igdir.edu.tr.
Ahmet MusmulDepartment of Medical Services and Techniques, Faculty of Medicine, Eskişehir Osmangazi University, Eskişehir, Türkiye.

Funding

Siirt University, Scientific Research Projects Unit 2021-SİÜEĞT-17
6 · The paper itself

Abstract

The purpose of this study is to measure the effects of acrylamide (AA) on bone marrow and blood and the protective efficacy of boric acid (B) in rats. The animals were divided into five groups: control, B, low-dose B + AA, and high-dose B + AA. After the 15 th day of the experiment, their blood and bone marrow were harvested to be kept for hematological analyses. While white blood cells (WBC) increased following the administration of AA, bodyweight, red blood cells, platelets, hemoglobin, hematocrit, and bone marrow nucleated cell counts significantly decreased in number. Conversely, bodyweight and all these hematological parameters significantly increased apart from WBC in the B + AA groups AA when compared to the control. However, high-dose B was more effective than low-dose B in preventing AA-induced bone marrow and hematological damage. The present study suggests that B treatment could help protect bone marrow and hematological parameters against AA-induced toxicity.

Indexed as

AcrylamideBone MarrowBoric AcidsBoronAdministration, OralAnimalsHematocritMaleRatsRats, WistarAcrylamideboric acidBoric AcidsBoronAcrylamideBoronHematologic toxicityMyelotoxicityRats

Identifiers

PMID40193000
PMCPMC12602650

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.