Evidence map›Paper›PMID 40192987›Full record

ArticleInternational urology and nephrology2025

Enhanced recovery after surgery in laparoscopic kidney donor nephrectomy: the role of quadratus lumborum and transversus abdominis plane block.

Cristian A Hernandez-Gaytán, Jorge Alcacio-Mendoza, Jose de Jesus Cendejas-Gomez, Javier Gonzalez-Chavira, Yoztinn Bernal-Benitez, Humberto Zavaleta-Guraieb, Cassandra Dominguez-Hernández, Diana García-Campos, Rafael P Leal-Villalpando, Gerardo Tena-González Méndez and 2 more

Abstract read
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In one paragraph

Article in International urology and nephrology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors.

Cristian A Hernandez-GaytánDepartment of Urology, Instituto Nacional de Ciencias Médicas y Nutrición Salvador Zubirán, Vasco de Quiroga 15 Belisario Dominguez Seccion XVI, Tlalpan, Mexico City, Mexico.ORCID https://orcid.org/0009-0003-2740-7476
Jorge Alcacio-MendozaDepartment of Urology, Instituto Nacional de Ciencias Médicas y Nutrición Salvador Zubirán, Vasco de Quiroga 15 Belisario Dominguez Seccion XVI, Tlalpan, Mexico City, Mexico.
Jose de Jesus Cendejas-GomezDepartment of Urology, Instituto Nacional de Ciencias Médicas y Nutrición Salvador Zubirán, Vasco de Quiroga 15 Belisario Dominguez Seccion XVI, Tlalpan, Mexico City, Mexico.
Javier Gonzalez-ChaviraDepartment of Urology, Instituto Nacional de Ciencias Médicas y Nutrición Salvador Zubirán, Vasco de Quiroga 15 Belisario Dominguez Seccion XVI, Tlalpan, Mexico City, Mexico.
Yoztinn Bernal-BenitezDepartment of Urology, Instituto Nacional de Ciencias Médicas y Nutrición Salvador Zubirán, Vasco de Quiroga 15 Belisario Dominguez Seccion XVI, Tlalpan, Mexico City, Mexico.
Humberto Zavaleta-GuraiebDepartment of Urology, Instituto Nacional de Ciencias Médicas y Nutrición Salvador Zubirán, Vasco de Quiroga 15 Belisario Dominguez Seccion XVI, Tlalpan, Mexico City, Mexico.
Cassandra Dominguez-HernándezDepartment of Urology, Instituto Nacional de Ciencias Médicas y Nutrición Salvador Zubirán, Vasco de Quiroga 15 Belisario Dominguez Seccion XVI, Tlalpan, Mexico City, Mexico.
Diana García-CamposDepartment of Anesthesiology, Instituto Nacional de Ciencias Médicas y Nutrición Salvador Zubirán, Vasco de Quiroga 15, Tlalpan, Mexico City, Mexico.
Rafael P Leal-VillalpandoDepartment of Anesthesiology, Instituto Nacional de Ciencias Médicas y Nutrición Salvador Zubirán, Vasco de Quiroga 15, Tlalpan, Mexico City, Mexico.
Gerardo Tena-González MéndezDepartment of Urology, Instituto Nacional de Ciencias Médicas y Nutrición Salvador Zubirán, Vasco de Quiroga 15 Belisario Dominguez Seccion XVI, Tlalpan, Mexico City, Mexico.
Bernardo Gabilondo-PliegoDepartment of Urology, Instituto Nacional de Ciencias Médicas y Nutrición Salvador Zubirán, Vasco de Quiroga 15 Belisario Dominguez Seccion XVI, Tlalpan, Mexico City, Mexico.
Francisco Rodríguez-CovarrubiasDepartment of Urology, Instituto Nacional de Ciencias Médicas y Nutrición Salvador Zubirán, Vasco de Quiroga 15 Belisario Dominguez Seccion XVI, Tlalpan, Mexico City, Mexico. frodriguez.covarrubias@gmail.com.ORCID https://orcid.org/0000-0003-0056-7886

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

purposeLiving donor kidney transplants (LDKTs) represent nearly 35% of all kidney transplants, with laparoscopic living donor nephrectomy (LLDN) being the standard surgical approach. Enhanced Recovery After Surgery (ERAS) protocols have demonstrated better perioperative outcomes in LLDN. This study evaluates the impact of an ERAS protocol on postoperative opioid consumption and length of stay (LOS) compared to standard of care (SC).

methodsThis experimental, prospective study included patients undergoing LLDN at a tertiary care center. The ERAS protocol included preoperative nutritional optimization, ultrasound-guided transversus abdominis plane (TAP) and quadratus lumborum (QL) block for multimodal analgesia, opioid restriction and early oral intake, and mobilization. The SC group followed traditional perioperative care.

resultsA total of 286 patients, 86 patients in ERAS group and 172 in SC group were analyzed. ERAS group significantly reduced LOS (1.59 ± 0.7 days vs 3.39 ± 1.85 days in the SC group, p < 0.001) and opioid consumption on postoperative day (POD) 1 and 2. The pain scores on POD 1 were lower in the ERAS group, with no differences by POD 2 or 3. There were no differences in operative time, complication rates, or renal function at 6 months between groups.

conclusionThe ERAS protocol demonstrated significant advantages over SC, including shorter LOS and reduced opioid use, without compromising safety or long-term renal outcomes. These findings support the routine adoption of ERAS protocols in LLDN as a safe and feasible approach.

Indexed as

Enhanced Recovery After SurgeryKidney TransplantationLaparoscopyNephrectomyNerve BlockPostoperative PainAbdominal MusclesAdultAnalgesics, OpioidFemaleHumansLength of StayLiving DonorsMaleMiddle AgedProspective StudiesAnalgesics, OpioidKidney transplantOpioidsQuadratus lumborum blockRegional anesthesiaTransversus abdominis plane block

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.