SynthesisSports medicine - open2025
Physical Activity, Air Pollution, and Mortality: A Systematic Review and Meta-analysis.
Synthesis in Sports medicine - open, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
5 citing papers in PubMed.
- Modelled Physical Activity Benefits and PMToxics · 2026Article
- Vitamin D deficiency modifies the association between ambient PMNutrition research and practice · 2026Article
- Air Pollution and Incident Cardiovascular Disease: Modification by Genetic Susceptibility and the Mitigating Role of Physical Activity.Journal of the American Heart Association · 2026Article
- Joint exposure to PMFrontiers in public health · 2025Article
- Does Exercise Overcome Pollution? Why Physical Activity is Still Our Best Medicine.Open respiratory archivesArticle
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
10 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundAs whether the positive effects of physical activity on mortality outweigh the negative effects of exposure to pollution is still under debate, we conducted a systematic review and meta-analysis on the risk of mortality for combined exposure to physical activity and air pollution.
methodsPubMed, Cochrane, Embase and ScienceDirect databases were searched for studies assessing the risk of mortality for combined exposure to physical activity and air pollution.
resultsWe included eight studies for a total of 1,417,945 individuals (mean 57.7 years old, 39% men) - 54,131 died. We confirmed that air pollution increased the risk of mortality by 36% (OR 1.36, 95CI 1.05-1.52), whereas physical activity in a non-polluted environment decreased the risk of mortality by 31% (OR 0.69, 95CI 0.42-0.95). Our meta-analysis demonstrated that combined exposure to physical activity and air pollution decreased the risk of mortality by 26% (OR 0.74, 95CI 0.63-0.85). This risk decreased whatever the level of physical activity: by 19% (OR 0.81, 95CI 0.69-0.93) for low, by 32% (OR 0.68, 95CI 0.44-0.93) for moderate, and by 30% (OR 0.70, 95CI 0.49-0.91) for high physical activity in air pollution.
conclusionWe confirmed that air pollution increased mortality by 36% in our meta-analysis. Despite the controversial benefit-risk, we demonstrated a reduction of mortality by 26% for combined exposure to physical activity and air pollution - nearly comparable to the reduction of mortality when practicing physical activity without air pollution (- 31%). However, the limited number of included studies precluded the demonstration of a dose-response relationship between levels of physical activity and air pollution, and reduction of mortality.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.