ReviewCellular and molecular life sciences : CMLS2025
Mosquito immune responses to Plasmodium parasites that limit malaria transmission.
Review in Cellular and molecular life sciences : CMLS, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
5 citing papers in PubMed.
- Cross-species TNF-α signaling in mosquitoes promotes malaria transmission.EMBO reports · 2026Article
- Demystifying Plasmodium development within the Anopheles mosquito.Current opinion in microbiology · 2026Review
- MaRNAV-1, an intracellular virus ofbioRxiv : the preprint server for biology · 2026Article
- Evolutionary Trajectory ofBiomedicines · 2025Review
- Comparative immunological roles of TEP1 inFrontiers in immunology · 2025Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
3 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
The mosquito immune system is a major barrier that malaria parasites must overcome for their successful development and disease transmission. At each developmental stage in the vector, Plasmodium parasites can be potentially targeted by the mosquito innate immune responses, which involve epithelial, humoral, and cellular components. The immune response to Plasmodium ookinetes can be powerful and some of the underlying effector mechanisms are well characterized. However, the defense responses to oocysts and sporozoites appear to be less effective and are less well understood. Plasmodium parasites are under constant pressure to avoid elimination by evading and/or manipulating the mosquito immune system. Understanding the intricate interaction between Plasmodium parasites and the mosquito immune system is fundamental to understand the epidemiology of malaria transmission and to devise innovative control strategies.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.