ArticleInvestigative ophthalmology & visual science2025
Evaluating the Volume of Eyes With Pathologic Myopia Using 3D MRI.
Article in Investigative ophthalmology & visual science, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.
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Who cites it
1 citing paper in PubMed.
- The Eye-Brain Axis in High Myopia: From Retinal Deformation to Cortical Network Reorganization.Eye and brain · 2026Review
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Authors and funding
11 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Purpose: To determine the volume of eyes and its relationship to the shape and the presence of posterior staphylomas in patients with high myopia (HM). Methods: We studied 370 eyes of 199 patients with HM (refractive error >8.00 diopters [D] or an axial length ≥26.5 mm) and 44 eyes of 35 control patients without HM (refractive error from -7.50 to +2.50 D). Magnetic resonance imaging (MRI) of the ocular orbit was used to measure the volume of the eye using three-dimensional (3D) MRI. Reconstructed 3D images of eye were classified according to symmetry and steepness of the posterior curvature. Results: The mean volume was 12.42 ± 2.40 mL of the 370 HM eyes and 9.67 ± 1.41 mL of the 44 non-HM eyes. Thus, the volume of the HM eyes was 1.3 times larger than the mean volume of the non-HM eyes. The mean volume of the eye was significantly smaller in the cylindrically shaped and larger in barrel-shaped eyes than the eyes with other shapes. The mean eye volume in the HM eyes with a posterior staphyloma was not significantly different from that of HM eyes without a posterior staphyloma. Conclusions: The volume of HM eyes is larger than non-HM eyes and is associated with steepness of posterior curvature but not with the presence of a posterior staphyloma, suggesting that local outward protrusion of the posterior eye wall is not directly caused by global expansion of eyes and should be monitored specifically in HM eyes.
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