Evidence map›Paper›PMID 40192602›Full record

ArticleAngewandte Chemie (International ed. in English)2025

Synthesis and Characterization of Photoswitchable Covalent Ligands for the β

Ulrike Wirth, Eduard Neu, Davide Provasi, Steffen Feustel, Maximilian F Schmidt, Harald Hübner, Dorothée Weikert, Marta Filizola, Burkhard König, Peter Gmeiner

Abstract read
In one paragraph

Article in Angewandte Chemie (International ed. in English), 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Structural Mechanism of an Efficacy Photoswitch Targeting the βAngewandte Chemie (International ed. in English) · 2026
    Article
  2. Photo-clenbuterol: Optical Control of βJournal of medicinal chemistry · 2025
    Article
  3. Synthesis and Characterization of Photoswitchable Covalent Ligands for the βAngewandte Chemie (International ed. in English) · 2025
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Ulrike Wirth *Faculty of Chemistry and Pharmacy, University of Regensburg, 93053, Regensburg, Germany.
Eduard Neu *Department of Chemistry and Pharmacy, Friedrich-Alexander-Universität Erlangen-Nürnberg, 91058, Erlangen, Germany.
Davide ProvasiDepartment of Pharmacological Sciences, Icahn School of Medicine at Mount Sinai, New York, NY, USA.
Steffen FeustelDepartment of Chemistry and Pharmacy, Friedrich-Alexander-Universität Erlangen-Nürnberg, 91058, Erlangen, Germany.
Maximilian F SchmidtDepartment of Chemistry and Pharmacy, Friedrich-Alexander-Universität Erlangen-Nürnberg, 91058, Erlangen, Germany.
Harald HübnerDepartment of Chemistry and Pharmacy, Friedrich-Alexander-Universität Erlangen-Nürnberg, 91058, Erlangen, Germany.
Dorothée WeikertDepartment of Chemistry and Pharmacy, Friedrich-Alexander-Universität Erlangen-Nürnberg, 91058, Erlangen, Germany.
Marta FilizolaDepartment of Pharmacological Sciences, Icahn School of Medicine at Mount Sinai, New York, NY, USA.
Burkhard KönigFaculty of Chemistry and Pharmacy, University of Regensburg, 93053, Regensburg, Germany.
Peter GmeinerDepartment of Chemistry and Pharmacy, Friedrich-Alexander-Universität Erlangen-Nürnberg, 91058, Erlangen, Germany.

Funding

COVID and Translational Science supercomputer (CATS)S10OD030463 · OD · ICAHN SCHOOL OF MEDICINE AT MOUNT SINAI · PI KOVATCH, PATRICIA · 2021 to 2021
$2.0M
Fonds der Chemischen IndustrieGerman Research FoundationNIH HHS S10 OD030463Studienstiftung des Deutschen Volkes
6 · The paper itself

Abstract

The β

Indexed as

Adrenergic beta-2 Receptor AgonistsReceptors, Adrenergic, beta-2HumansKineticsLigandsMolecular Dynamics SimulationMolecular StructurePhotochemical ProcessesThermodynamicsAdrenergic beta-2 Receptor AgonistsLigandsReceptors, Adrenergic, beta-2Computational chemistryCovalent ligandGPCRMedicinal chemistryPhotopharmacology

Identifiers

PMID40192602
PMCPMC12144893

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.