Evidence map›Paper›PMID 40192483›Full record

ReviewAntimicrobial agents and chemotherapy2025

Regulation, structure, and activity of the

Logan G Kavanaugh, Megan E Hinrichsen, Christine M Dunham, Graeme L Conn

Abstract readReview
PubMed Full text at PMC Publisher
In one paragraph

Review in Antimicrobial agents and chemotherapy, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed.

  1. Article
  2. Article
  3. Review
  4. Antibiotic resistance inFrontiers in microbiology · 2026
    Review
  5. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Logan G KavanaughDepartment of Biochemistry, Emory University School of Medicine, Atlanta, Georgia, USA.ORCID 0000-0001-9467-7175
Megan E HinrichsenDepartment of Chemistry, Emory University, Atlanta, Georgia, USA.
Christine M DunhamDepartment of Chemistry, Emory University, Atlanta, Georgia, USA.ORCID 0000-0002-8821-688X
Graeme L ConnDepartment of Biochemistry, Emory University School of Medicine, Atlanta, Georgia, USA.ORCID 0000-0002-2419-380X

Funding

Training Program in Biochemistry, Cell and Molecular BiologyT32GM135060 · NIGMS · EMORY UNIVERSITY · PI Lawrence H. Boise, ANITA H. CORBETT · 2020 to 2026
$2.8M
Regulation and mechanism of RND-mediated antibiotic efflux in PseudomonasR01AI185192 · NIAID · EMORY UNIVERSITY · PI Graeme L Conn, Christine M Dunham · 2024 to 2026
$2.0M
Biological Discovery through Chemical Innovation Training Program at Emory UniversityT32GM152344 · NIGMS · EMORY UNIVERSITY · PI Simon B. Blakey, ELLEN J. HESS · 2024 to 2026
$976k
Molecular basis for substrate discrimination by transporter protein MexY of the MexXY-OprM efflux pump in Pseudomonas aeruginosaF31GM143891 · NIGMS · EMORY UNIVERSITY · PI KAVANAUGH, LOGAN GLENN · 2021 to 2024
$165k
NIAID NIH HHS R01 AI185192NIGMS NIH HHS F31 GM143891NIGMS NIH HHS T32 GM135060NIGMS NIH HHS T32 GM152344
6 · The paper itself

Abstract

The current crisis in bacterial antibiotic resistance can be attributed to the overuse (or misuse) of these essential medicines in healthcare and agriculture, coupled with the slowed progression of new drug development. In the versatile, opportunistic pathogen

Indexed as

antibiotic resistanceeffluxPseudomonasresistance-nodulation-division (RND)

Identifiers

PMID40192483
PMCPMC12057347

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.