Evidence map›Paper›PMID 40192467›Full record

ArticleAntimicrobial agents and chemotherapy2025

Identification and characterization of a novel major facilitator superfamily (MFS) efflux pump conferring multidrug resistance in

Honghao Huang, Yiyi Chen, Lingxuan Zhang, Peng Wan, Yan Chen, Yafei Li, Zhenling Zeng

Abstract read
In one paragraph

Article in Antimicrobial agents and chemotherapy, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Genomic and clinical characteristics ofMicrobiology spectrum · 2026
    Article
  2. The Evolution of Symbiosis inBiomolecules · 2026
    Review
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Honghao Huang *Guangdong Provincial Key Laboratory of Veterinary Pharmaceutics Development and Safety Evaluation, National Risk Assessment Laboratory for Antimicrobial Resistance of Animal Original Bacteria, College of Veterinary Medicine, South China Agricultural University, Guangzhou, China.ORCID 0000-0002-1939-2417
Yiyi Chen *Department of Infectious Diseases, Sir Run Run Shaw Hospital, Zhejiang University School of Medicine, Hangzhou, Zhejiang, China.
Lingxuan ZhangInstitute of Quality Standard and Monitoring Technology for Agro-products, Guangdong Academy of Agricultural Sciences, Guangzhou, Guangdong, China.
Peng WanGuangdong Provincial Key Laboratory of Veterinary Pharmaceutics Development and Safety Evaluation, National Risk Assessment Laboratory for Antimicrobial Resistance of Animal Original Bacteria, College of Veterinary Medicine, South China Agricultural University, Guangzhou, China.
Yan ChenDepartment of Infectious Diseases, Sir Run Run Shaw Hospital, Zhejiang University School of Medicine, Hangzhou, Zhejiang, China.ORCID 0000-0002-7679-1713
Yafei LiInstitute of Quality Standard and Monitoring Technology for Agro-products, Guangdong Academy of Agricultural Sciences, Guangzhou, Guangdong, China.ORCID 0000-0002-1347-2459
Zhenling ZengGuangdong Provincial Key Laboratory of Veterinary Pharmaceutics Development and Safety Evaluation, National Risk Assessment Laboratory for Antimicrobial Resistance of Animal Original Bacteria, College of Veterinary Medicine, South China Agricultural University, Guangzhou, China.ORCID 0000-0002-1103-7170

Funding

National Natural Science Foundation of China 32121004Special Fund for Science and Technology Innovation Strategy-Construction of the Main Force of of Agriculture Scientific Research R2023PY-JX012
6 · The paper itself

Abstract

A novel major facilitator superfamily (MFS) efflux pump in

Indexed as

Anti-Bacterial AgentsBacterial ProteinsDrug Resistance, Multiple, BacterialMembrane Transport ProteinsStaphylococcus aureusStaphylococcus epidermidisAnimalsBiofilmsHumansMicrobial Sensitivity TestsPhylogenyPlasmidsStaphylococcal InfectionsSwineAnti-Bacterial AgentsBacterial ProteinsMembrane Transport Proteinsantimicrobial resistanceefflux pumpmajor facilitator superfamilyStaphylococcus aureusStaphylococcus epidermidis

Identifiers

PMID40192467
PMCPMC12057375

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.