ArticleChemMedChem2025
In Vitro and In Vivo Photothermal and Photoacoustic Activities of Polymeric Nanoparticles Loaded with Nickel, Palladium, and Platinum-Bis(dithiolene) Complexes.
Article in ChemMedChem, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
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Who cites it
1 citing paper in PubMed.
- Novel Strategies for Precision Diagnosis and Treatment of Prostate Cancer Based on Multifunctional Nanocarrier Systems.International journal of nanomedicine · 2026Review
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Authors and funding
11 authors.
Funding
Abstract
The development of nanosystems with enhanced photothermal and photoacoustic properties is crucial for advancing theranostic applications in cancer therapy. This study explores polymeric nanoparticles (NPs) constituted by a biocompatible poly(ethylene glycol)-block-poly(benzyl malate) copolymer and loaded with metal-bis(dithiolene) complexes (M = Ni, Pd, Pt). These NPs, prepared via a robust nanoprecipitation method, demonstrate uniform morphology, efficient encapsulation (≈70%), and tailored near-infrared (NIR) optical absorption properties. Photothermal and photoacoustic evaluations reveal superior performance of palladium-loaded NPs, offering high contrast for imaging and significant temperature increases under NIR laser irradiation. Cytotoxicity assays confirm their nontoxicity without laser exposure, while effective cancer cell eradication is achieved upon irradiation at power densities ≥2 W cm
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