Evidence map›Paper›PMID 40192338›Full record

SynthesisDiagnostic and interventional radiology (Ankara, Turkey)2025

Diagnostic performance of radiomics analysis for pulmonary cancer airway spread: a systematic review and meta-analysis.

Jie Chen, Xinyue Zhang, Chi Xu, Kefu Liu

Abstract readSystematic ReviewMeta-Analysis
In one paragraph

Synthesis in Diagnostic and interventional radiology (Ankara, Turkey), 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed.

  1. Article
  2. Article
  3. Review
  4. Article
  5. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Jie ChenThe Affiliated Suzhou Hospital of Nanjing Medical University, Department of Radiology, Suzhou, China.ORCID 0009-0009-9350-2475
Xinyue ZhangZhejiang University School of Medicine Sir Run Run Shaw Hospital, Department of Medical Record, Hangzhou, China.ORCID 0009-0009-1046-6828
Chi XuThe Affiliated Suzhou Hospital of Nanjing Medical University, Department of Radiology, Suzhou, China.ORCID 0009-0000-5978-5269
Kefu LiuThe Affiliated Suzhou Hospital of Nanjing Medical University, Department of Radiology, Suzhou, China.ORCID 0009-0000-6299-0685

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

purposeSpread through air spaces (STAS) is a unique metastatic pattern of pulmonary cancer closely associated with patient prognosis. This study evaluates the application of radiomics in the diagnosis of pulmonary cancer STAS through meta-analysis and explores its clinical significance and potential limitations.

methodsWe systematically searched the PubMed, Embase, and Cochrane Central Register of Controlled Trials databases for relevant studies between inception and April 1, 2024. The main evaluation indicators included sensitivity, specificity, positive likelihood ratio, negative likelihood ratio, and area under the curve (AUC). A total of 18 studies, covering 6,642 lung cancer cases, were included in the systematic review.

resultsIn the development cohort, the sensitivity of radiomics for diagnosing STAS was 0.80 [95% confidence interval (CI): 0.75-0.84;

conclusionRadiomics analysis demonstrates important clinical significance in the diagnosis of pulmonary cancer STAS, with promising sensitivity and specificity results in both development and validation cohorts. CLINICAL SIGNIFICANCE: While radiomics analysis offers valuable diagnostic insights for STAS in pulmonary cancer, its limitations must be carefully considered. Future research should focus on addressing these limitations and further exploring the application prospects of radiomics in lung cancer diagnosis and treatment.

Indexed as

Lung NeoplasmsTomography, X-Ray ComputedFemaleHumansMaleRadiomicsSensitivity and Specificitycomputed tomographyLung cancermeta-analysisradiomicsspread through air spaces

Identifiers

PMID40192338
PMCPMC12057535

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.