Evidence map›Paper›PMID 40192272›Full record

ArticleNeuropathology and applied neurobiology2025

Intramuscular Nerve Bundles Reflect TDP-43 Pathology in the Medulla and Spinal Cord of ALS Patients.

Takashi Kurashige, Tomomi Murao, Yuhei Kanaya, Yoriko Dodo, Tomohito Sugiura, Kazuya Kuraoka, Tomohiko Ohshita

Abstract read
In one paragraph

Article in Neuropathology and applied neurobiology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Proteomic Identification of ALDOA as a Pathogenic TDP-43 Interaction Partner in ALS.Degenerative neurological and neuromuscular disease · 2025
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Takashi KurashigeDepartment of Neurology, NHO Kure Medical Center and Chugoku Cancer Center, Kure, Japan.ORCID https://orcid.org/0000-0002-5206-5979
Tomomi MuraoDepartment of Neurology, NHO Kure Medical Center and Chugoku Cancer Center, Kure, Japan.
Yuhei KanayaDepartment of Neurology, NHO Kure Medical Center and Chugoku Cancer Center, Kure, Japan.
Yoriko DodoDepartment of Neurology, NHO Kure Medical Center and Chugoku Cancer Center, Kure, Japan.
Tomohito SugiuraDepartment of Neurology, NHO Kure Medical Center and Chugoku Cancer Center, Kure, Japan.
Kazuya KuraokaDepartment of Diagnostic Pathology, NHO Kure Medical Center and Chugoku Cancer Center, Kure, Japan.
Tomohiko OhshitaDepartment of Neurology, NHO Kure Medical Center and Chugoku Cancer Center, Kure, Japan.

Funding

ALS foundation by Japan ALS AssociationDaiichi Sankyo Foundation of Life ScienceJapan ALS AssociationKato Memorial Trust for Nanbyo ResearchKurozumi Medical FoundationOkinaka Memorial Institute for Medical ResearchSENSHIN Medical Research FoundationTakeda Science FoundationTakeda Science Foundation, and Tsuchiya FoundationTsuchiya Foundation
6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

amyotrophic lateral sclerosis (ALS)anterior hornhypoglossal nucleiintramuscular nerve bundlestransactive response DNA‐binding protein 43 (TDP‐43)

Identifiers

PMID40192272
PMCPMC11974360

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.