Evidence map›Paper›PMID 40192234›Full record

ArticleChemSusChem2025

Mechanochemical Generation of Active Pd/BippyPhos Catalyst for Efficient CN Cross-Coupling in Air.

Deniz Karabiyikli, Alexandre Saad, Sokaina Hammoud, Séverine Schneider, Romuald Manca, Jesus Raya, Martine Schmitt, Frédéric Bihel

Abstract read
In one paragraph

Article in ChemSusChem, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Deniz KarabiyikliLaboratoire d'Innovation Thérapeutique, UMR7200, CNRS, Université de Strasbourg, Faculté de pharmacie - 74, route du Rhin, 67401, Illkirch, France.
Alexandre SaadLaboratory of Membranes Biophysics and NMR, UMR7177, Institut de Chimie, CNRS, Université de Strasbourg, 4 rue Blaise Pascal, 67070, Strasbourg, France.
Sokaina HammoudLaboratoire d'Innovation Thérapeutique, UMR7200, CNRS, Université de Strasbourg, Faculté de pharmacie - 74, route du Rhin, 67401, Illkirch, France.
Séverine SchneiderLaboratoire d'Innovation Thérapeutique, UMR7200, CNRS, Université de Strasbourg, Faculté de pharmacie - 74, route du Rhin, 67401, Illkirch, France.
Romuald MancaLaboratory of Membranes Biophysics and NMR, UMR7177, Institut de Chimie, CNRS, Université de Strasbourg, 4 rue Blaise Pascal, 67070, Strasbourg, France.
Jesus RayaLaboratory of Membranes Biophysics and NMR, UMR7177, Institut de Chimie, CNRS, Université de Strasbourg, 4 rue Blaise Pascal, 67070, Strasbourg, France.
Martine SchmittLaboratoire d'Innovation Thérapeutique, UMR7200, CNRS, Université de Strasbourg, Faculté de pharmacie - 74, route du Rhin, 67401, Illkirch, France.
Frédéric BihelLaboratoire d'Innovation Thérapeutique, UMR7200, CNRS, Université de Strasbourg, Faculté de pharmacie - 74, route du Rhin, 67401, Illkirch, France.ORCID https://orcid.org/0000-0002-4122-0929

Funding

Agence Nationale de la Recherche ANR-10-IDEX-0002Agence Nationale de la Recherche ANR-17-EURE-0022Agence Nationale de la Recherche ANR-20-SFRI-0012Centre National de la Recherche ScientifiqueInstitut National de la Santé et de la Recherche MédicaleUniversité de Strasbourg
6 · The paper itself

Abstract

Carbonnitrogen (CN) bond-forming cross-coupling reactions catalyzed by palladium-based systems, known as Buchwald-Hartwig aminations, are widely used in natural product synthesis, pharmaceuticals, agrochemicals, and materials science. However, these reactions typically require organic solvents and inert atmospheres, such as argon, increasing environmental, health, and safety concerns. Using electron-rich bulky phosphine ligands in combination with [Pd(π-cinnamyl)Cl]

Indexed as

ball millcross‐coupling reactionsolid‐state NMRsolid‐state reactionssustainable chemistry

Identifiers

PMID40192234
PMCPMC12232107

What OpenQuestion holds

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LicenceCC BY
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.