Evidence map›Paper›PMID 40192212›Full record

ArticleJournal of the American Geriatrics Society2025

Scaling Alzheimer's Care: The Case for Specialized Treatment Clinics.

Eric D Vidoni, Adam C Parks, Amanda Brunette, Katelynn Kreszyn, Ryan A Townley, Anne K Arthur, Lindsey Gillen, Jaime Perales Puchalt, Tina Lewandowski, Dinesh P Mudaranthakam and 4 more

Abstract read
In one paragraph

Article in Journal of the American Geriatrics Society, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed.

  1. Article
  2. Brain health care accelerator: A primary care-centered model for scaling dementia diagnosis and care.Alzheimer's & dementia : the journal of the Alzheimer's Association · 2026
    Article
  3. Article
  4. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

14 authors.

Eric D VidoniUniversity of Kansas Medical Center, Kansas City, Kansas, USA.ORCID 0000-0001-5181-7131
Adam C ParksUniversity of Kansas Medical Center, Kansas City, Kansas, USA.
Amanda BrunetteUniversity of Kansas Medical Center, Kansas City, Kansas, USA.
Katelynn KreszynThe University of Kansas Health System, Kansas City, Kansas, USA.
Ryan A TownleyUniversity of Kansas Medical Center, Kansas City, Kansas, USA.
Anne K ArthurUniversity of Kansas Medical Center, Kansas City, Kansas, USA.
Lindsey GillenThe University of Kansas Health System, Kansas City, Kansas, USA.
Jaime Perales PuchaltUniversity of Kansas Medical Center, Kansas City, Kansas, USA.ORCID 0000-0003-1013-7847
Tina LewandowskiUniversity of Kansas Medical Center, Kansas City, Kansas, USA.
Dinesh P MudaranthakamUniversity of Kansas Medical Center, Kansas City, Kansas, USA.
Jill K MorrisUniversity of Kansas Medical Center, Kansas City, Kansas, USA.
T Ryan SmithUniversity of Kansas Medical Center, Kansas City, Kansas, USA.
Jennifer WoodwardUniversity of Kansas Medical Center, Kansas City, Kansas, USA.
Jeffrey M BurnsUniversity of Kansas Medical Center, Kansas City, Kansas, USA.

Funding

University of Kansas Alzheimer's Disease Research Center (KU ADRC)P30AG072973 · NIA · UNIVERSITY OF KANSAS MEDICAL CENTER · PI JEFFREY Murray BURNS, RUSSELL H. SWERDLOW · 2021 to 2026
$25.3M
Aligning PCPs and Patients with Alzheimer's Research Efforts: MyAlliance for Cognitive HealthR24AG063724 · NIA · UNIVERSITY OF KANSAS MEDICAL CENTER · PI BURNS, JEFFREY MURRAY, VIDONI, ERIC DENNIS · 2020 to 2022
$4.1M
Prescribing Smart Aging: Integrating Health Systems with Community-Based Lifestyle InterventionsR01AG052954 · NIA · UNIVERSITY OF KANSAS MEDICAL CENTER · PI BURNS, JEFFREY MURRAY · 2017 to 2021
$2.9M
Multidisciplinary Research Training Program in Alzheimer's Disease and Related DisordersT32AG078114 · NIA · UNIVERSITY OF KANSAS MEDICAL CENTER · PI Sandra A Billinger, Eric Dennis Vidoni · 2022 to 2026
$1.2M
NIA NIH HHS P30 AG072973NIA NIH HHS R01 AG052954NIA NIH HHS R24 AG063724NIA NIH HHS T32 AG078114
6 · The paper itself

Abstract

backgroundThe approval of amyloid-targeting monoclonal antibodies has transformed Alzheimer's disease (AD) treatment, shifting the field from symptomatic management to targeting the underlying pathology. These therapies require specialized care models to manage the selection, treatment, and monitoring of eligible patients.

methodsHere, we describe the implementation of the Anti-Amyloid Treatment Clinic (KU-AATC) at the University of Kansas Health System, a dedicated clinic model designed to streamline access to amyloid-clearing therapies and to provide safe, efficient patient care. We detail the KU-AATC's structured approach, including a multidisciplinary team with advanced practice providers (APPs), leading patient evaluation and shared decision-making, and tailored workflows to ensure timely access to treatment. We review data from the clinic's first 18 months.

resultsThe KU-AATC model demonstrates a feasible approach to managing the complex needs of amyloid-targeting therapy for AD.

conclusionsOur findings suggest that a specialized clinic structure can support safe, accessible, and efficient care for AD patients, potentially serving as a scalable model for healthcare systems adapting to the demands of emerging AD treatments. Expanding similar clinics may address neurologist shortages and improve equitable access to advanced therapies.

Indexed as

Alzheimer DiseaseAmbulatory Care FacilitiesAgedHumansKansasPatient Care TeamAlzheimer's diseaseamyloid‐beta immunotherapymultidisciplinary care models

Identifiers

PMID40192212
PMCPMC12353897

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.