Evidence map›Paper›PMID 40192114›Full record

SynthesisMedicina oral, patologia oral y cirugia bucal2025

Inferior alveolar nerve damage related to dental implant placement. A systematic review and meta-analysis.

J-F Peña-Cardelles, J Markovic, S Akhondi, I Pedrinaci, A Lanis, G-O Gallucci

Abstract readSystematic ReviewMeta-Analysis
In one paragraph

Synthesis in Medicina oral, patologia oral y cirugia bucal, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed, 1 synthesis or guideline pooled it.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

J-F Peña-CardellesDepartment of Restorative Dentistry and Biomaterials Sciences Harvard School of Dental Medicine 188 Longwood Avenue, Boston, MA, USA Juan_PenaCardelles@hsdm.harvard.edu; juanfranciscopenacardelles@gmail.com.
J Markovic
S Akhondi
I Pedrinaci
A Lanis
G-O Gallucci

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundA concern associated with implant placement is the potential occurrence of neurovascular lesions and subsequent development of sensory alterations in patients undergoing implant placements. The objective of this review is to evaluate the incidence of neurosensory alterations based on the proximity between the implant and the mandibular canal Material and Methods: A systematic review was conducted in MEDLINE, Web of Science, and Scopus. Studies with common variables were selected to conduct a meta-analysis. The patient classification was based on the mandibular canal-implant distance. Neurosensory alteration percentages were calculated for each study and group.

resultsThe findings indicate significant correlations between implant placement proximity and neurosensory risks. The incidence of neurosensory alterations in patients with implants placed at a distance ≥ 2 mm from the mandibular canal was 0%. Similarly, for distances between 1-2 mm from the mandibular canal, the incidence remained at 0%. However, for implants placed at a distance of 0-1 mm from the mandibular canal, the incidence of neurosensory alterations was 68%. Additionally, patients with implants that intruded into the canal had an incidence of 53% in the development of neurosensorial alterations.

conclusionsA distance of 1 mm from the mandibular canal might be safe. Implants placed at a distance less than 1 mm from the mandibular canal exhibit neurosensory alterations. Clinicians should be aware of the potential risk of nerve injury and adopt appropriate precautions, including meticulous preoperative planning and three-dimensional radiographic images.

Indexed as

Dental ImplantationDental ImplantsMandibular Nerve InjuriesHumansDental Implants

Identifiers

PMID40192114
PMCPMC12221155

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.