Evidence map›Paper›PMID 40192111›Full record

SynthesisMedicina oral, patologia oral y cirugia bucal2025

Survival rate and marginal bone loss in titanium vs titanium-zirconia single-unit narrow diameter implants. A systematic review and Meta-analysis of prospective studies.

J-F Peña-Cardelles, S Akhondi, J Markovic, K Pala, A Lanis, G-O Gallucci

Abstract readSystematic ReviewMeta-AnalysisComparative Study
In one paragraph

Synthesis in Medicina oral, patologia oral y cirugia bucal, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Review
  2. Article
  3. Observational
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

J-F Peña-CardellesDepartment of Restorative Dentistry and Biomaterials Sciences Harvard School of Dental Medicine 188 Longwood Avenue, Boston, MA, USA Juan_PenaCardelles@hsdm.harvard.edu; juanfranciscopenacardelles@gmail.com.
S Akhondi
J Markovic
K Pala
A Lanis
G-O Gallucci

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundImplant-supported single-unit restorations present a predictable and widely used treatment option to replace missing teeth. Narrow-diameter implants provide a viable treatment option for clinical scenarios with limited bone availability, minimizing the need for bone augmentation procedures. This systematic review aims to assess implant survival and implant marginal bone loss among different single-unit narrow implant diameters and between titanium single-unit and titanium-zirconia single-unit narrow implants. MATERIAL AND

methodsThis article was structured according to the Preferred Reporting Items for Systematic Reviews and Meta-Analyses (PRISMA®) Included criteria were randomized clinical trials (RCTs) and clinical prospective studies with at least 10 patients, a mean follow-up period of at least 12 months, and assessing single-tooth implants with a diameter of 3.5 mm or less.

resultsTwelve included articles were prospective clinical studies, while 3 articles were randomized controlled clinical studies. There are no significant differences in the comparison between the 2.9-3.0 mm group and the 3.3-3.5 mm group (p=0.933). Both groups had a 99% survival (95% CI, 99.9%-100%). Titanium-zirconia implants presented a mean of marginal bone loss of -0,37 mm (CI, 95%: -0,53 to -0,20) meanwhile, titanium implants had a mean of marginal bone loss of -0,43 mm (CI95%:-0,71 to -0,28).

conclusionsThe findings reveal no significant differences between 2.9-3.3mm and 3.3-3.5mm groups within narrow implants. Both titanium and titanium-zirconia alloys in narrow implants, exhibit comparable high survival rates and minimal marginal bone loss, showcasing their feasibility as a viable treatment alternative in scenarios with limited space or inadequate bone for regular diameter implants.

Indexed as

Alveolar Bone LossDental ImplantsDental Implants, Single-ToothDental Restoration FailureTitaniumZirconiumDental Prosthesis DesignHumansProspective StudiesSurvival RateDental ImplantsTitaniumZirconiumzirconium oxide

Identifiers

PMID40192111
PMCPMC12221152

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.