Evidence map›Paper›PMID 40191923›Full record

ReviewEuropean journal of clinical investigation2025

Applications, challenges and future directions of artificial intelligence in cardio-oncology.

Francesco Ravera, Nicolò Gilardi, Alberto Ballestrero, Gabriele Zoppoli

Abstract readReview
In one paragraph

Review in European journal of clinical investigation, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 16 papers.

0numbers the graph read from it
0cells of the map it votes in
16citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

16 citing papers in PubMed.

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  8. Integrated Cardio-oncology Service.Cardiac failure review · 2026
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Francesco RaveraDepartment of Internal Medicine and Medical Specialties, University of Genoa, Genoa, Italy.ORCID https://orcid.org/0000-0003-3856-7910
Nicolò GilardiDepartment of Internal Medicine and Medical Specialties, University of Genoa, Genoa, Italy.
Alberto BallestreroDepartment of Internal Medicine and Medical Specialties, University of Genoa, Genoa, Italy.
Gabriele ZoppoliDepartment of Internal Medicine and Medical Specialties, University of Genoa, Genoa, Italy.

Funding

5x1000 IRCCS, Progetti di Rilevante Interesse Nazionale (PRIN) ID 20223XM78ZAssociazione Italiana per la Ricerca sul Cancro IG 21761
6 · The paper itself

Abstract

backgroundThe management of cardiotoxicity related to cancer therapies has emerged as a significant clinical challenge, prompting the rapid growth of cardio-oncology. As cancer treatments become more complex, there is an increasing need to enhance diagnostic and therapeutic strategies for managing their cardiovascular side effects.

objectiveThis review investigates the potential of artificial intelligence (AI) to revolutionize cardio-oncology by integrating diverse data sources to address the challenges of cardiotoxicity management.

methodsWe explore applications of AI in cardio-oncology, focusing on its ability to leverage multiple data sources, including electronic health records, electrocardiograms, imaging modalities, wearable sensors, and circulating serum biomarkers.

resultsAI has demonstrated significant potential in improving risk stratification and longitudinal monitoring of cardiotoxicity. By optimizing the use of electrocardiograms, non-invasive imaging, and circulating biomarkers, AI facilitates earlier detection, better prediction of outcomes, and more personalized therapeutic interventions. These advancements are poised to enhance patient outcomes and streamline clinical decision-making.

conclusionsAI represents a transformative opportunity in cardio-oncology by advancing diagnostic and therapeutic capabilities. However, successful implementation requires addressing practical challenges such as data integration, model interpretability, and clinician training. Continued collaboration between clinicians and AI developers will be essential to fully integrate AI into routine clinical workflows.

Indexed as

Antineoplastic AgentsArtificial IntelligenceCardiotoxicityCardiovascular DiseasesMedical OncologyNeoplasmsBiomarkersCardiologyCardio-OncologyElectrocardiographyElectronic Health RecordsHumansRisk AssessmentWearable Electronic DevicesAntineoplastic AgentsBiomarkersartificial intelligencecardio‐oncologydeep learningelectrocardiogramimagingmachine learning

Identifiers

PMID40191923
PMCPMC11973867

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.