ArticleJournal of surgical case reports2025
Challenges in diagnosis and treatment of recurrent ameloblastic carcinoma in the maxilla: case report and narrative review of current literatures.
Article in Journal of surgical case reports, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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Abstract
Ameloblastic carcinoma (AC) is a malignant transformation of benign ameloblastoma originating from epithelial cells of tooth enamel and has the potential for metastasis. A 42-year-old male experienced three recurrences of AC and hospitalized for surgical treatment. He was initially diagnosed as maxillary nasal sinus squamous cell carcinoma. However, the patient experienced a third recurrence, and additional examinations revealed the diagnosis of AC. The patient underwent right subtotal maxillectomy through Weber Ferguson incision with Dieffenbach extension. Followed by a post-operative radiotherapy course. This case report discusses the histopathological findings and current challenges of diagnosing and managing the recurrent AC. The findings suggest that the use of chemotherapy, radiotherapy, or a combination to surgical interventions is still restricted. Evidence available is insufficient to draw definitive conclusions regarding their safety and efficacy of different treatment modalities in AC treatment.
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