Evidence map›Paper›PMID 40191586›Full record

SynthesisNAR genomics and bioinformatics2025

Meta-analysis of genomic characteristics for antiviral influenza defective interfering particle prioritization.

Jens J G Lohmann, Mia Le, Fadi G Alnaji, Olga Zolotareva, Jan Baumbach, Tanja Laske

Abstract readMeta-Analysis
PubMed Full text at PMC Publisher
In one paragraph

Synthesis in NAR genomics and bioinformatics, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Jens J G LohmannInstitute for Computational Systems Biology, University of Hamburg, 22761 Hamburg, Germany.ORCID 0000-0001-7463-5971
Mia LeInstitute for Computational Systems Biology, University of Hamburg, 22761 Hamburg, Germany.
Fadi G AlnajiA*STAR Infectious Diseases Labs (A*STAR ID Labs), Agency for Science, Technology and Research (A*STAR), 8A Biomedical Grove, Immunos #05-13, 138648 Singapore, Singapore.ORCID 0000-0002-2893-9832
Olga ZolotarevaInstitute for Computational Systems Biology, University of Hamburg, 22761 Hamburg, Germany.ORCID 0000-0002-9424-8052
Jan BaumbachInstitute for Computational Systems Biology, University of Hamburg, 22761 Hamburg, Germany.ORCID 0000-0002-0282-0462
Tanja LaskeInstitute for Computational Systems Biology, University of Hamburg, 22761 Hamburg, Germany.ORCID 0000-0002-7922-7595

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Defective interfering particles (DIPs) are viral deletion mutants that hamper virus replication and are, thus, potent novel antiviral agents. To evaluate possible antiviral treatments, we first need to get a deeper understanding of DIP characteristics. Thus, we performed a meta-analysis of 20 already published sequencing datasets of influenza A and B viruses (IAV and IBV) from

Indexed as

Antiviral AgentsDefective Interfering VirusesGenome, ViralInfluenza A virusInfluenza B virusAnimalsHumansInfluenza, HumanVirus ReplicationAntiviral Agents

Identifiers

PMID40191586
PMCPMC11970370

What OpenQuestion holds

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LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.