ArticlePrzeglad gastroenterologiczny2025
Natural history and progression risk factors of ulcerative proctitis: a retrospective study from a single tertiary centre in Poland.
Article in Przeglad gastroenterologiczny, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.
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Who cites it
3 citing papers in PubMed.
- Efficacy of Microencapsulated Sodium Butyrate as Add-On Therapy in Inducing Remission in Patients with Mild-To-Moderate Ulcerative Colitis: Results From a Multi-Center, Double-Blind, Randomized, Placebo-Controlled Study.Medical science monitor : international medical journal of experimental and clinical research · 2025Trial
- Multicentre retrospective real-world evidence study evaluating the effectiveness and safety of mirikizumab in patients with moderately to severely active ulcerative colitis.Przeglad gastroenterologiczny · 2026Article
- Fecal butyric acid as a predictive biomarker of endoscopic remission in inflammatory bowel disease: a multicenter prospective study.Przeglad gastroenterologiczny · 2025Article
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Authors and funding
7 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Introduction: Ulcerative proctitis is a chronic disease, characterized by lower risk of complications and less aggressive treatment in comparison to other forms of ulcerative colitis. Therefore, the key issue is to predict the natural course of the disease and protect against proximal spread of inflammatory lesions in the future. Aim: To identify risk factors for progression of ulcerative proctitis and investigate the natural history of the disease. Material and methods: We performed a retrospective study and included patients with ulcerative proctitis, diagnosed between January 2010 and December 2020, who suffered from ulcerative proctitis for at least 1 year. The collected data were then subjected to statistical analysis. Results: We identified 116 cases of ulcerative proctitis in patients aged between 19 and 84 years. Proximal extension of the disease occurred in 65 (56%) people - left sided colitis developed in 55 (85%) and pancolitis in 10 (15%) patients. We detected many progression risk factors of ulcerative proctitis, among which the most meaningful were Mayo Endoscopic Score at levels 2 and 3 at onset ( Conclusions: According to our study, early identification of progression risk factors in ulcerative proctitis is crucial for the future outcomes of the disease. The proper treatment at onset is relevant in preventing the progression of inflammatory lesions and the development of disease complications.
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