Evidence map›Paper›PMID 40191389›Full record

ArticleImaging science in dentistry2025

Comparative accuracy of artificial intelligence-based AudaxCeph software, Dolphin software, and the manual technique for orthodontic landmark identification and tracing of lateral cephalograms.

Maryam Foroozandeh, Fatemeh Salemi, Abbas Shokri, Nasrin Farhadian, Nesa Aeini, Roghayyeh Hassanzadeh

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Article in Imaging science in dentistry, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

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0cells of the map it votes in
2citing papers in PubMed
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1 · What the graph read from it

What it found

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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

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Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

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4 · The record

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PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Maryam ForoozandehDepartment of Oral and Maxillofacial Radiology, Dental School, Dental Research Center, Hamadan University of Medical Sciences, Hamadan, Iran.ORCID https://orcid.org/0000-0002-4143-2112
Fatemeh SalemiDepartment of Oral and Maxillofacial Radiology, Dental School, Dental Research Center, Hamadan University of Medical Sciences, Hamadan, Iran.ORCID https://orcid.org/0000-0002-0534-3446
Abbas ShokriDepartment of Oral and Maxillofacial Radiology, Dental School, Dental Research Center, Hamadan University of Medical Sciences, Hamadan, Iran.ORCID https://orcid.org/0000-0002-3434-3672
Nasrin FarhadianDepartment of Orthodontics, School of Dentistry, Dental Research Center, Hamadan University of Medical Sciences, Hamadan, Iran.ORCID https://orcid.org/0000-0001-7611-0685
Nesa AeiniFarhangian Dental Clinic, Hamadan, Iran.ORCID https://orcid.org/0009-0008-4336-701X
Roghayyeh HassanzadehStudent Research Committee, Hamadan University of Medical Sciences, Hamadan, Iran.ORCID https://orcid.org/0000-0003-0715-6916

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Purpose: The aim of this study was to compare the accuracy of AI-based AudaxCeph software, Dolphin software, and the manual technique for identifying orthodontic landmarks and tracing lateral cephalograms. Materials and Methods: In this cross-sectional study, 23 anatomical landmarks were identified on 60 randomly selected lateral cephalograms, and 5 dental indices, 4 skeletal indices, and 1 soft tissue index were measured. Each cephalogram was traced using 4 different methods: manually, with the Dolphin software, with the AudaxCeph software automatically, and with the AudaxCeph software in semi-automatic mode. The intra-class correlation coefficient (ICC) and Bland-Altman plots were used to evaluate the agreement between methods. Inter-observer and intra-observer agreements, calculated using the ICC, confirmed the accuracy, reliability, and reproducibility of the results. Results: There was strong agreement among the AudexCeph (semi-automated or automated) AudaxCeph, Dolphin, and manual methods in measuring orthodontic indices, with ICC values consistently above 0.90. Bland-Altman plots confirmed satisfactory agreement between both versions of AudaxCeph (semi-automated and automated) with the manual method, with mean differences close to 0 and about 95% of data points within the limits of agreement. However, the semi-automated AudaxCeph showed greater agreement and precision than the automated version, as indicated by narrower limits of agreement. The ICC values for inter-observer and intra-observer agreements exceeded 0.98 and 0.99, respectively. Conclusion: The semi-automated AudaxCeph software offers a robust and cost-effective solution for cephalometric analysis. Its high accuracy and affordability make it a compelling alternative to Dolphin software and the manual method.

Indexed as

Anatomic LandmarksArtificial IntelligenceCephalometryDeep LearningDiagnostic ImagingOrthodontics

Identifiers

PMID40191389
PMCPMC11966017

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.