ArticleACS omega2025
Investigation of Cytotoxic and Antimicrobial Effects of Polyanhydride-Based Poly[(maleic anhydride)-
Article in ACS omega, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
0 citing papers in PubMed.
No citing paper in PubMed yet.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
3 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Studies aimed at increasing the efficacy of chemotherapeutic drugs and reducing or completely eliminating their side effects are frequently encountered. In our study, we considered methotrexate (MTX), which is in the category of anticarcinogenic and anti-inflammatory drugs, and gemcitabine (GEM), which is used in the treatment of breast, testicular, ovarian, etc. cancers. GEM, which is used in the treatment of breast, testicular, ovarian, etc. cancers, was covalently bonded to maleic anhydride vinyl acetate (MAVA) copolymer, and new polymer-drug conjugates (MAVA-MTX and MAVA-GEM) were obtained to reduce or eliminate the side effects of these drugs and to investigate the cytotoxic and antimicrobial effects of the new conjugates. The conjugation reaction was carried out in the presence of a triethylamine catalyst in dimethylformamide medium at 70 °C. Chemical structure elucidation of the copolymer (MAVA) and conjugates (MAVA-MTX and MAVA-GEM) was carried out by Fourier transform infrared (FTIR) and Nuclear Magnetic Resonance (
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.