Evidence map›Paper›PMID 40191310›Full record

ArticleACS omega2025

Instantaneous Hydrolysis of Methyl Paraoxon Nerve Agent Simulant Is Catalyzed by Nontoxic Aminoguanidine Imines.

Emmanuel Kingsley Darkwah, Puspa Aryal, Chi Zhang, Charles B Musgrave, William A Goddard, V Prakash Reddy

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in ACS omega, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Emmanuel Kingsley DarkwahDepartment of Chemistry, Missouri University of Science and Technology, Rolla, Missouri 65409, United States.
Puspa AryalDepartment of Chemistry, Missouri University of Science and Technology, Rolla, Missouri 65409, United States.
Chi ZhangMaterials and Process Simulation Center (MSC), California Institute of Technology, Pasadena, California 91125, United States.
Charles B MusgraveMaterials and Process Simulation Center (MSC), California Institute of Technology, Pasadena, California 91125, United States.ORCID https://orcid.org/0000-0002-3432-0817
William A GoddardMaterials and Process Simulation Center (MSC), California Institute of Technology, Pasadena, California 91125, United States.ORCID https://orcid.org/0000-0003-0097-5716
V Prakash ReddyDepartment of Chemistry, Missouri University of Science and Technology, Rolla, Missouri 65409, United States.ORCID https://orcid.org/0000-0003-3011-4175

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Exposure to organophosphate-based nerve agents and pesticides poses health and security threats to civilians, soldiers, and first responders. Thus, there is a need to develop effective decontamination agents that are nonhazardous to human health. To address this, we demonstrate that instantaneous hydrolysis of methyl paraoxon (Me-POX), a nerve agent simulant, can be achieved in the presence of aminoguanidine imines at pH 10: ● the pyridine-4-aldehyde aminoguanidine-imine (

Identifiers

PMID40191310
PMCPMC11966261

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.