ArticleInternational journal of general medicine2025
Factors Influencing the Length of Emergency Intensive Care Unit Stay in Adult Tetanus Patients.
Article in International journal of general medicine, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.
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Who cites it
2 citing papers in PubMed.
- Clinical and epidemiological profile of patients with accidental tetanus in a referral hospital: a 13-year historical series.Infection · 2026Article
- Clinical characteristics, management, and outcomes of severe tetanus in the intensive care unit.BMC infectious diseases · 2026Observational
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Authors and funding
9 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Objective: Tetanus remains a public health problem in developing countries. Patients with severe tetanus require long-term access to emergency medical resources. Here, we identified the risk factors for a prolonged length of stay (LOS) in the emergency intensive care unit (EICU) in adult tetanus patients. Methods: We conducted a retrospective study using data from adult tetanus patients admitted to the EICU in our hospitals. K‒M analysis was used for LOS analysis in the EICU, and the Log rank test was used for comparisons between groups. Cox proportional hazards regression model analyses were used to assess significant factors associated with LOS in the EICU. Results: A total of 81 tetanus patients were included in the study. The patients had an average age of 59.39 ± 10.90 years (SD). The mean LOS was 18.1 days (median, 16.0 days; range, 0.6 days to 50.0 days). From 15 related factors, we identified two independent factors for prolonging the LOS of tetanus patients in the EICU: tracheotomy and mechanical ventilation. The risk of EICU retention in patients with mechanical ventilation was 55.3% greater than that in patients without mechanical ventilation (HR=0.447, 95% CI: 0.227-0.880, P=0.020); the risk of EICU retention was 86.2% greater in patients with tracheotomy than in those without tracheotomy (HR=0.138, 95% CI: 0.058-0.328, P<0.001). Conclusion: Tracheotomy and mechanical ventilation support were associated with increased LOS in the EICU in adult tetanus patients, independent of the tetanus antitoxin dose. Clinicians must focus on spasm control and optimize airway management in tetanus patients in the EICU.
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