Evidence map›Paper›PMID 40191225›Full record

ArticleCase reports in dentistry2025

Periapically Extruded Calcium Silicate Cements in Retreated Teeth: A Case Report and Literature Review.

Jelena Vidas Hrstić, Mario Jakobović, Sanja Šegović, Gabriel Tokić, Ivana Brekalo Pršo

Abstract readCase Reports
In one paragraph

Article in Case reports in dentistry, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Jelena Vidas HrstićDepartment of Endodontics and Restorative Dentistry, Faculty of Dental Medicine, University of Rijeka, Rijeka, Croatia.ORCID https://orcid.org/0000-0001-7278-5837
Mario JakobovićDepartment of Dental Medicine, Faculty of Dental Medicine and Health, Josip Juraj Strossmayer University of Osijek, Osijek, Croatia.
Sanja ŠegovićDepartment of Endodontics and Restorative Dentistry, School of Dental Medicine, University of Zagreb, Zagreb, Croatia.ORCID https://orcid.org/0009-0005-1954-1186
Gabriel TokićFaculty of Dental Medicine, University of Rijeka, Rijeka, Croatia.
Ivana Brekalo PršoDepartment of Endodontics and Restorative Dentistry, Faculty of Dental Medicine, University of Rijeka, Rijeka, Croatia.ORCID https://orcid.org/0000-0001-9303-0409

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Calcium silicate-based materials, known for their bioactive properties, are increasingly being used in endodontic therapy. Accidental extrusion of these materials into the periapical tissue is a relatively common phenomenon that can impede periapical healing. The aim of this article is to present three endodontically retreated case reports with moderate to extensive periapical lesions and to review the literature on this topic. The comprehensive search and analysis of the relevant literature included a review of 51 articles, of which nine case reports/series from 2010 to 2023 were considered. Based on the summarized data, over 80% of the retreated cases showed complete healing of the periapical lesions, while the success rate in initially treated teeth was over 90%. Healing of periapical lesions is the most common therapeutic outcome, even in cases where extrusion occurs. Despite this conclusion, extrusion of materials into periapical tissues should be avoided. Further case reports on the extrusion of calcium silicate-based materials other than MTA are recommended. When evaluating the success rate of periapical healing in such cases, it is recommended to extend the follow-up periods to several years.

Indexed as

bioceramic sealercalcium silicate cementsmineral trioxide aggregateroot canal retreatmentsealer extrusion

Identifiers

PMID40191225
PMCPMC11971511

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.