ArticleFrontiers in psychiatry2025
The impact of depression on the quality of life of lung cancer patients undergoing chemotherapy: mediating effects of perceived social support.
Article in Frontiers in psychiatry, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers, 1 of them a synthesis that pooled it.
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Who cites it
5 citing papers in PubMed, 1 synthesis or guideline pooled it.
- Tobacco Use, Stigma, and Coping in Lung Cancer: A Systematic Review of Their Psychosocial Interactions and Clinical Implications.Current oncology (Toronto, Ont.) · 2026Pooled it
- The elicitation of quality of life preferences for lung cancer treatment from the perspective of patients and treating physicians: results of two discrete choice experiments.The European journal of health economics : HEPAC : health economics in prevention and care · 2026Article
- Experiences of psychosomatic symptoms and self-management strategies among patients with advanced lung cancer undergoing chemotherapy: a qualitative study based on symptom management theory.Frontiers in public health · 2026Article
- Mental health in female breast cancer survivors post-mastectomy: A structural model based on Roy's adaptation model.Asia-Pacific journal of oncology nursing · 2025Article
- Exploring the relationship between postoperative psychological resilience and symptom burden in esophageal cancer patients.Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer · 2025Article
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5 authors.
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Abstract
Background: Quality of life (QOL) in patients undergoing chemotherapy for lung cancer has been a key research area. Numerous studies have examined the relationships among depression, perceived social support (PSS), and QOL. However, the mechanisms underlying PSS in lung cancer patients receiving chemotherapy remain underexplored. Objective: To investigate the mediating role of PSS in the relationship between depression and QOL in lung cancer patients undergoing chemotherapy. Methods: A convenience sample of 390 lung cancer patients undergoing chemotherapy was selected from the outpatient clinics and wards of the Department of Oncology at a tertiary hospital in Deyang City between January 2024 and June 2024. Participants completed a general information questionnaire, Self-Rating Depression Scale (SDS), Multidimensional Scale of Perceived Social Support (MPSSS), and Functional Assessment of Cancer Therapy-Lung Cancer (FACT-L) scale. SPSS 26.0 was used to analyze correlations between depression, PSS, and QOL, while AMOS 26.0 assessed the mediating effect of PSS on the relationship between depression and QOL. Results: The mean scores for depression, PSS, and QOL were 39.79 ± 11.63, 68.96 ± 13.09, and 66.43 ± 23.67, respectively. Pearson's correlation analysis showed that depression was negatively correlated with QOL (r = -0.319, Conclusion: Depression in lung cancer patients undergoing chemotherapy directly impacts QOL and indirectly affects it through PSS. Clinically, healthcare providers should address depression in these patients and offer psychological support and interventions as needed. Additionally, medical institutions can implement targeted strategies to help patients build a strong social support system, reduce negative emotions, enhance psychological well-being, and improve overall QOL.
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