Evidence map›Paper›PMID 40191104›Full record

Reviewnpj biological physics and mechanics2025

Premetastatic niche mechanics and organotropism in breast cancer.

Sarah Libring, Cynthia A Reinhart-King

Abstract readReview
In one paragraph

Review in npj biological physics and mechanics, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors.

Sarah LibringDepartment of Bioengineering, Rice University, Houston, TX USA.
Cynthia A Reinhart-KingDepartment of Bioengineering, Rice University, Houston, TX USA.

Funding

Matrix Accumulation in the Metastatic NicheK00CA264734 · NCI · VANDERBILT UNIVERSITY · PI Sarah Libring · 2023 to 2026
$409k
NCI NIH HHS K00 CA264734
6 · The paper itself

Abstract

Numerous physical and mechanical changes occur in the premetastatic niche. Here, we review the mechanics of the premetastatic niche and how the altered extracellular matrix and cancer cell mechanics may play a role in organotropism in breast cancer. Future research into premetastatic niche development and organotropic cell behavior should address physical alterations and biomechanical effects to the same rigor that biochemical alterations are studied.

Indexed as

Cell migrationMechanisms of disease

Identifiers

PMID40191104
PMCPMC11968405

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.