Evidence map›Paper›PMID 40191030›Full record

ArticleInterface focus2025

Perfusion-mechanics coupling of the hippocampus.

Caitlin Maria Neher, Em Triolo, Fargol RezayAraghi, Oleksandr Khegai, Priti Balchandani, Matthew McGarry, Mehmet Kurt

Abstract read
In one paragraph

Article in Interface focus, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Caitlin Maria NeherUniversity of Washington, Seattle, WA, USA.ORCID https://orcid.org/0009-0007-8249-6319
Em TrioloUniversity of Washington, Seattle, WA, USA.
Fargol RezayAraghiUniversity of Washington, Seattle, WA, USA.
Oleksandr KhegaiIcahn School of Medicine at Mount Sinai, New York, NY, USA.
Priti BalchandaniIcahn School of Medicine at Mount Sinai, New York, NY, USA.
Matthew McGarryDartmouth College, Hanover, NH, USA.
Mehmet KurtUniversity of Washington, Seattle, WA, USA.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The hippocampus is a highly scrutinized brain structure due to its entanglement in multiple neuropathologies and vulnerability to metabolic insults. This study aims to non-invasively assess the perfusion-mechanics relationship of the hippocampus in the healthy brain across magnetic resonance imaging sequences and magnetic field strengths. In total, 17 subjects (aged 22-35, 7 males/10 females) were scanned with magnetic resonance elastography and arterial spin labelling acquisitions at 3T and 7T in a baseline physiological state. No significant differences in perfusion or stiffness were observed across magnetic field strengths or acquisitions. The hippocampus had the highest vascularity within the deep grey matter, followed closely by the caudate nucleus and putamen. We discovered a positive perfusion-mechanics correlation in the hippocampus across both 3T and 7T groups, with a highly significant correlation overall (

Indexed as

brain mechanicsbrain pulsatilityhippocampusMR elastographyneuroimagingperfusion

Identifiers

PMID40191030
PMCPMC11969186

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.