Evidence map›Paper›PMID 40191027›Full record

ArticleInterface focus2025

Non-invasive quantification of pressure drops in stenotic intracranial vessels: using deep learning-enhanced 4D flow MRI to characterize the regional haemodynamics of the pulsing brain.

Ali El Ahmar, Susanne Schnell, Sameer A Ansari, Ramez N Abdalla, Alireza Vali, Maria Aristova, Michael Markl, Patrick Winter, David Marlevi

Abstract read
In one paragraph

Article in Interface focus, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Article
  2. Article
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Ali El AhmarDepartment of Medical Physics, Faculty of Mathematics and Natural Sciences, University of Greifswald, Greifswald, Germany.ORCID https://orcid.org/0009-0004-0275-193X
Susanne SchnellDepartment of Medical Physics, Faculty of Mathematics and Natural Sciences, University of Greifswald, Greifswald, Germany.ORCID https://orcid.org/0000-0001-6009-4756
Sameer A AnsariDepartment of Radiology, Northwestern University, Feinberg School of Medicine, Chicago, IL, USA.
Ramez N AbdallaDepartment of Radiology, Northwestern University, Feinberg School of Medicine, Chicago, IL, USA.
Alireza ValiQualcomm Technologies, Inc., San Diego, CA, USA.
Maria AristovaDepartment of Neurology and Neurological Surgery, Northwestern University, Feinberg School of Medicine, Chicago, IL, USA.
Michael MarklDepartment of Radiology, Northwestern University, Feinberg School of Medicine, Chicago, IL, USA.
Patrick WinterDepartment of Medical Physics, Faculty of Mathematics and Natural Sciences, University of Greifswald, Greifswald, Germany.
David MarleviDepartment of Molecular Medicine and Surgery, Karolinska Institutet, Stockholm, Sweden.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Stenosis of major intracranial arteries is a significant cause of stroke, with assessment of trans-stenotic pressure drops being a key marker of functional stenosis severity. Non-invasive methods for quantifying intracranial pressure changes are hence crucial; however, the narrow and tortuous cerebrovascular network poses challenges to traditional assessment methods such as transcranial Doppler. This study investigates the use of novel deep learning-enhanced super-resolution (SR) four-dimensional (4D) flow magnetic resonance imaging (MRI) in combination with a physics-informed virtual work-energy relative pressure technique to quantify pressure drops across stenotic intracranial arteries. Performance was validated in intracranial-mimicking

Indexed as

4D flow MRIintracranial atherosclerotic diseasepulsing brainsuper-resolutiontrans-stenotic pressure drop

Identifiers

PMID40191027
PMCPMC11969193

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.