Evidence map›Paper›PMID 40191024›Full record

ArticleInterface focus2025

Intracranial pulse wave velocity using 4D flow MRI: method comparison and covariate analysis.

Sergio Dempsey, Soroush Safaei, Samantha J Holdsworth, Gonzalo D Maso Talou

Abstract read
In one paragraph

Article in Interface focus, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Sergio DempseyAuckland Bioengineering Institute, University of Auckland, 70 Symonds Street, Auckland 1010, New Zealand.ORCID https://orcid.org/0000-0003-1738-3047
Soroush SafaeiAuckland Bioengineering Institute, University of Auckland, 70 Symonds Street, Auckland 1010, New Zealand.ORCID https://orcid.org/0000-0001-5734-243X
Samantha J HoldsworthMātai Medical Research Institute, 466 Childers Road, Gisborne 4010, New Zealand.ORCID https://orcid.org/0000-0002-2929-1169
Gonzalo D Maso TalouAuckland Bioengineering Institute, University of Auckland, 70 Symonds Street, Auckland 1010, New Zealand.ORCID https://orcid.org/0000-0002-5208-992X

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Intracranial pulse wave velocity (PWV) offers the potential to enhance neurovascular care when evaluating cerebrovascular disease. Using 4D flow MRI, we measured PWV in the intracranial vasculature stemming from the internal carotids and basilar arteries using three popular techniques: cross-correlation, waveform optimization and time-to-upstroke which have all been used intracranially, but never compared. Near-perfect agreement between cross-correlation and waveform optimization methods was observed, while the time-to-upstroke method estimated a significantly larger PWV and was more prone to non-physiological values in a cohort of 21 healthy individuals aged 48 ± 18 years. We then analysed our cohort PWV using an ensemble approach given the current lack of methodological consensus. This analysis identified two consistent findings. First, internal carotids measure significantly higher PWV than basilar vascular networks (3.64 ± 1.47 versus 2.53 ± 1.39 m s

Indexed as

4D flowarterial stiffnesscerebral blood flowmagnetic resonance imagingpulse wave velocity

Identifiers

PMID40191024
PMCPMC11969195

What OpenQuestion holds

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LicenceCC BY
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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.