ArticleCureus2025
Neuroinvasive West Nile Encephalitis Presenting With Seizures and Acute Flaccid Paralysis: A Case Report.
Article in Cureus, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
2 citing papers in PubMed.
- Pharmaceutical Strategies for West Nile Virus in Europe, an Underrecognized Cause of Severe Disease and Mortality in Older Adults: From Supportive Care to Antiviral Development.Pharmaceuticals (Basel, Switzerland) · 2026Review
- West Nile virus unmasked: from gene variability to future challenges.Frontiers in cellular and infection microbiology · 2025Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
5 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
West Nile encephalitis (WNE) is a serious neurological disorder caused by the West Nile virus (WNV), a mosquito-borne flavivirus. The virus is mainly transmitted to humans through bites from infected Culex mosquitoes, with birds acting as the primary reservoir hosts. While most WNV infections are asymptomatic or cause a mild febrile illness (West Nile fever), a small subset of cases progresses to severe neuroinvasive disease, such as encephalitis, meningitis, or acute flaccid paralysis. WNE is marked by brain inflammation, resulting in high fever, headache, neck stiffness, disorientation, tremors, seizures, and paralysis. Advanced age and immunocompromised states are important risk factors for severe disease. There is no specific antiviral treatment for WNE, and management remains supportive. Preventive measures, such as mosquito control and public awareness, are essential for reducing the incidence of this disease. WNV has a global distribution, with outbreaks reported in North America, Europe, Africa, and Asia, making it a significant public health issue.
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Identifiers
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.