Evidence map›Paper›PMID 40190975›Full record

ArticleCureus2025

Clinical Profile of Acute Kidney Injury in Type 2 Diabetes Mellitus Adult Patients Presenting With Diabetic Ketoacidosis: A Cross-Sectional Study.

Sajit Varghese, Anna Mary Thomas, Arjun V, Acsa J Solamon

Abstract read
In one paragraph

Article in Cureus, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Sajit VargheseDepartment of General Medicine, Pushpagiri Institute of Medical Sciences & Research Centre, Thiruvalla, IND.
Anna Mary ThomasDepartment of General Medicine, Pushpagiri Institute of Medical Sciences & Research Centre, Thiruvalla, IND.
Arjun VDepartment of General Medicine, Pushpagiri Institute of Medical Sciences & Research Centre, Thiruvalla, IND.
Acsa J SolamonDepartment of General Medicine, Pushpagiri Institute of Medical Sciences & Research Centre, Thiruvalla, IND.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectiveThe purpose of this cross-sectional study was to identify the characteristics of acute kidney injury (AKI) in adult patients with type 2 diabetes mellitus (T2DM) who were admitted with diabetic ketoacidosis (DKA). METHODOLOGY: One hundred patients were selected based on the inclusion and exclusion criteria. Kidney function was assessed using kidney estimated glomerular filtration rate (KeGFR) calculations based on the Kidney Disease: Improving Global Outcomes (KDIGO) criteria. Data collection included clinical, biological, and demographic information. Univariate and multivariate logistic regression analyses were performed, with a p-value of less than 0.05 considered statistically significant. The study also examined risk factors, intensive care unit (ICU) treatments, and clinical outcomes.

resultsAKI was significantly associated with ICU length of stay (p = 0.002), and all patients with prolonged ICU admission developed this condition. A higher incidence of AKI was observed in patients requiring mechanical ventilation, renal replacement therapy, or inotropic support. Among the 100 patients included in the study, 94 achieved clinical recovery, including 76 who had AKI, while six patients did not survive.

conclusionAKI is a common complication of DKA in adults with T2DM, particularly in hot climate regions. Most cases were detected within the first 24 hours, classified as stage 1 severity, and were pre-renal. Early detection plays a crucial role in preventing complications and improving patient recovery. KeGFR calculations proved an effective tool for monitoring kidney function changes in these patients.

Indexed as

acute kidney injury (aki)diabetic ketoacidosis (dka)icu length of stay (iculs)renal function assessmenttype 2 diabetes mellitus

Identifiers

PMID40190975
PMCPMC11972431

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