Evidence map›Paper›PMID 40190969›Full record

ArticleCureus2025

Glycoprotein Matrix-Bound Iron Improves Absorption Compared to Ferrous Bisglycinate Chelate and Ferrous Fumarate: A Randomized Crossover Trial.

Ariane H Secrest, Charlene Norgan Radler, Jaci Kelly, Nikolas Keratsopoulos, Alyssa Faterkowski, Katelyn Kolodziejczyk, Mathis Rollin, Robert Mills, Mandy E Parra, Ralf Jäger and 3 more

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Cureus, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors.

Ariane H SecrestEpidemiology and Public Health, University of Mary Hardin-Baylor, Belton, USA.
Charlene Norgan RadlerBurnett School of Medicine, Texas Christian University, Fort Worth, USA.
Jaci KellyExercise and Sports Science, Human Performance Lab, University of Mary Hardin-Baylor, Belton, USA.
Nikolas KeratsopoulosExercise and Sports Science, Human Performance Lab, University of Mary Hardin-Baylor, Belton, USA.
Alyssa FaterkowskiExercise and Sports Science, Human Performance Lab, University of Mary Hardin-Baylor, Belton, USA.
Katelyn KolodziejczykExercise and Sports Science, Human Performance Lab, University of Mary Hardin-Baylor, Belton, USA.
Mathis RollinExercise and Sports Science, Human Performance Lab, University of Mary Hardin-Baylor, Belton, USA.
Robert MillsExercise and Sports Science, Human Performance Lab, University of Mary Hardin-Baylor, Belton, USA.
Mandy E ParraExercise and Sports Science, Human Performance Lab, University of Mary Hardin-Baylor, Belton, USA.
Ralf JägerResearch and Development, Increnovo, LLC, Whitefish Bay, USA.
Martin PurpuaResearch and Development, Increnovo, LLC, Whitefish Bay, USA.
Grant M TinsleyKinesiology & Sport Management, Texas Tech University, Lubbock, USA.
Lem W TaylorPhysiology and Nutrition, University of Mary Hardin-Baylor, Belton, USA.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Introduction The biotransformation of minerals through glycosylation by microorganisms, such as yeast or probiotics, can produce nutrients bound to a food matrix, potentially enhancing their bioavailability. This study aimed to compare the absorption kinetics of iron bound to a glycoprotein matrix (GPM) with those of ferrous bisglycinate chelate (FBC) and ferrous fumarate (FF). Methods In a double-blind, crossover design, 17 participants ingested 11 mg of iron in one of three forms: GPM (Pharmachem Innovation, Kearny, NJ, USA), FBC (Ferrochel

Indexed as

absorptionironpostbioticsupplementwhole-food nutrients

Identifiers

PMID40190969
PMCPMC11972659

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.