Evidence map›Paper›PMID 40190931›Full record

ArticleCureus2025

Double Trouble: Herpes Simplex Encephalitis Triggering Autoimmune Encephalitis.

Somarajan Anandan, Parameswaran Krishnan

Abstract readCase Reports
In one paragraph

Article in Cureus, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors.

Somarajan AnandanNeurology, St. Joseph's Mission Hospital, Anchal, IND.
Parameswaran KrishnanNeurology, Indo American Brain and Spine Centre, Vaikom, IND.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Herpes simplex virus 1 (HSV1) is the most common cause of sporadic encephalitis worldwide. Even with optimal treatment, half of these patients experience significant neurological sequelae. A subset of these patients has recurrent neurological syndromes, occurring within two to three months of disease onset. Often, these patients show no evidence of recurrent herpes simplex virus (HSV) infection. Many develop antibodies against the N-methyl-D-aspartate receptor (NMDAR) . Here, we describe a case of anti-NMDAR encephalitis occurring almost a year after the onset of HSV encephalitis.

Indexed as

anti- nmda receptor encephalitisautoimmune encephalitisherpes simplex encephalitis (hse)post hse autoimmune encephalitispost hsv anti-nmda receptor encephalitis

Identifiers

PMID40190931
PMCPMC11972166

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.