Evidence map›Paper›PMID 40190611›Full record

ArticleSleep and biological rhythms2025

Choroid plexus enlargement in patients with rapid eye movement sleep behavior disorder: relevance to glymphatic system dysfunction.

Dong Ah Lee, Ho-Joon Lee, Kang Min Park

Abstract read
In one paragraph

Article in Sleep and biological rhythms, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

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Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

Dong Ah Lee *Department of Neurology, Haeundae Paik Hospital, Inje University College of Medicine, Haeundae-ro 875, Haeundae-gu, Busan, 48108 Republic of Korea.
Ho-Joon Lee *Department of Radiology, Haeundae Paik Hospital, Inje University College of Medicine, Busan, Republic of Korea.
Kang Min ParkDepartment of Neurology, Haeundae Paik Hospital, Inje University College of Medicine, Haeundae-ro 875, Haeundae-gu, Busan, 48108 Republic of Korea.ORCID 0000-0002-4229-7741

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Choroid plexus volume change has been suggested as a biomarker for the course of various neurological diseases. However, its role in sleep disorders remains unclear. We analyzed choroid plexus volume changes in patients with isolated rapid eye movement sleep behavior disorder (iRBD) compared with healthy controls. We enrolled 27 patients with iRBD and 27 healthy controls. All participants underwent brain magnetic resonance imaging (MRI), including three-dimensional T1-weighted imaging suitable for volumetric analysis. iRBD was diagnosed based on overnight polysomnography and corresponding clinical history. We compared the choroid plexus volume between patients with iRBD and healthy controls, and investigated the relationship between choroid plexus volume and polysomnographic findings. The mean choroid plexus volume was significantly larger in patients with iRBD than in healthy controls (2.379% vs. 2.116%,

Indexed as

Choroid plexusGlymphatic systemREM sleep behavior disorder

Identifiers

PMID40190611
PMCPMC11971069

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.