Evidence map›Paper›PMID 40190520›Full record

ArticleAfrican health sciences2024

The effectiveness of COVID-19 Heterologous Vaccination: the experience from a Regional Hospital in Cameroon.

Princewill Kum Unji, Alex Mambap Tatang, Samuel Angwafor, Loveline Lum Niba, Adji Minette Jaqueline Porro, Denis Nsame Nforniwe, Andreas Chiabi

Abstract read
In one paragraph

Article in African health sciences, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Princewill Kum UnjiUniversity of Bamenda, Clinical Sciences.
Alex Mambap TatangUniversity of Bamenda, Clinical Sciences.
Samuel AngwaforUniversity of Bamenda, Clinical Sciences.
Loveline Lum NibaUniversity of Bamenda, Clinical Sciences.
Adji Minette Jaqueline PorroBamenda Provincial Hospital.
Denis Nsame NforniweBamenda Provincial Hospital.
Andreas ChiabiUniversity of Bamenda, Clinical Sciences.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background: With most COVID-19 vaccines requiring at least 2 doses, heterologous vaccination will facilitate vaccination programs where vaccine supplies fluctuate. However, with insufficient data on effects of heterologous vaccination in our setting, people remain reluctant to mix. Objectives: We seek to assess the effects of heterologous vaccination on morbidity and mortality. Methods: This was a 7 months retrospective study for COVID-19 patients managed by the Bamenda Regional Hospital, Cameroon, running from the 18th August 2021 to 28 Results: Our 1254 participants had a mean age of 50.1(±19.6) years, we had 24 (1.9%) being fully vaccinated, where 7 (29.2%) took heterologous vaccines. Also, 721 (57.5%) had the moderate/severe form of the disease. Those fully vaccinated had lower odds of having severe disease (p=0.037). However, heterologous vaccination compared to homologous vaccination had no significant difference on morbidity (p=0.729). Among patients who died, none was fully vaccinated. Conclusion: The protective effect of vaccination on morbidity was similar in those with heterologous vaccination as well as those who took.

Indexed as

COVID-19COVID-19 VaccinesVaccinationAdultAgedCameroonFemaleHumansMaleMiddle AgedRetrospective StudiesSARS-CoV-2Vaccine EfficacyCOVID-19 VaccinesCOVID-19 vaccineheterologous vaccinationhomologous vaccination

Identifiers

PMID40190520
PMCPMC11970136

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.