Evidence map›Paper›PMID 40190445›Full record

ArticlePatient preference and adherence2025

Who is Seeking Traditional Chinese Medicine (TCM) for Cancer? Insights from a Large Cohort in a Rehabilitation Clinic.

Yong Zhang, Yiding Dai, Dan Kang, Qingsong Yu, Xiangxi Zhou, Xin Tian, Qiulong Chen, Yi Chen, Fang Liu, Qiuling Shi

Abstract read
In one paragraph

Article in Patient preference and adherence, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed.

  1. Article
  2. Dual trajectories of patient-reported fatigue and sleep disturbance in lung cancer survivors.Quality of life research : an international journal of quality of life aspects of treatment, care and rehabilitation · 2026
    Article
  3. Article
  4. Combination Therapy ofIntegrative cancer therapies
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Yong Zhang *School of Public Health, Chongqing Medical University, Chongqing, People's Republic of China.ORCID 0009-0009-4733-3084
Yiding Dai *Department of Integrated Traditional Chinese and Western Medicine, Sichuan Cancer Hospital & Institute, Sichuan Cancer Center, University of Electronic Science and Technology of China, Chengdu, Sichuan, People's Republic of China.ORCID 0009-0000-2142-058X
Dan Kang *School of Public Health, Chongqing Medical University, Chongqing, People's Republic of China.ORCID 0009-0001-8254-3417
Qingsong YuChengdu Center for Disease Control and Prevention, Chengdu, Sichuan, People's Republic of China.ORCID 0000-0001-6142-3339
Xiangxi ZhouSchool of Public Health, Chongqing Medical University, Chongqing, People's Republic of China.ORCID 0000-0002-7920-385X
Xin TianSchool of Public Health, Chongqing Medical University, Chongqing, People's Republic of China.ORCID 0009-0001-0972-9151
Qiulong ChenGraduate School, Chengdu Medical College, Chengdu, Sichuan, People's Republic of China.ORCID 0009-0009-3848-2619
Yi ChenSchool of Medicine, University of Electronic Science and Technology of China, Chengdu, Sichuan, People's Republic of China.ORCID 0009-0002-8179-2988
Fang LiuDepartment of Integrated Traditional Chinese and Western Medicine, Sichuan Cancer Hospital & Institute, Sichuan Cancer Center, University of Electronic Science and Technology of China, Chengdu, Sichuan, People's Republic of China.ORCID 0009-0000-0653-0692
Qiuling ShiSchool of Public Health, Chongqing Medical University, Chongqing, People's Republic of China.ORCID 0000-0003-0660-3809

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Purpose: Traditional Chinese Medicine (TCM) is widely used in cancer care, yet its utilization features are not well understood. By providing a comprehensive overview of the demographic and clinical characteristics, symptom burden, HRQoL, and TCM constitution of cancer patients seeking TCM treatment, we aim to offer insights into the integration of TCM into cancer care. Patients and Methods: The questionnaire collected data on demographic and clinical characteristics, the MD Anderson Symptom Inventory for Traditional Chinese Medicine (MDASI-TCM), the EuroQol-5Dimensions-5Levels (EQ-5D-5L), and the simplified version of the Constitution in Chinese Medicine Questionnaire (CCMQ). A descriptive analysis was conducted to profile the patients' status and expectations of TCM. Chi-square or Fisher exact tests were employed to compare the distribution of TCM constitutional types across different cancer diagnoses. Results: Among 3047 eligible patients, 2796 (median age 55) completed the questionnaire and were subsequently included in the analysis. The cohort was predominantly female (56.5%), with lung cancer being the most common primary diagnosis (25.2%). Furthermore, 86.7% of the patients presented with a good performance status (ECOG-PS ≤ 1). The main reasons patients sought TCM treatment were to alleviate cancer-related symptoms (59.4%) and enhance immune function (55.4%). The most prevalent symptoms (scored 1-10 on a 0-10 scale) were fatigue (81.1%), followed by disturbed sleep (81.0%), and dry mouth (78.2%). The mean and median EQ-5D-5L utility scores were 0.81 and 0.89, respectively. About 83.4% of cancer patients exhibited a deviation in TCM constitution, with Yang-deficiency being particularly common among them. Conclusion: This study highlights the symptom burden, HRQoL, TCM constitution, and characteristics of patients who pursue TCM treatment. It advances our understanding of TCM's role in cancer rehabilitation by shedding light on target population potential needs of care. The findings provide a foundation for developing evidence-based strategies to enhance TCM application in clinical settings, optimize resource allocation, and improve rehabilitation outcomes for cancer patients.

Indexed as

cancer rehabilitationhealth-related quality of lifepatient-reported outcomessymptom burdenTCM constitutiontraditional Chinese medicine

Identifiers

PMID40190445
PMCPMC11972600

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.