ArticleThe Pan African medical journal2024
Carriage of multiple resistance genes by community and hospital isolates of
Article in The Pan African medical journal, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.
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Who cites it
2 citing papers in PubMed.
- Genomic phylogeny, taxonomic classification, genetic landscape, and antibiotic resistance of clinicalFrontiers in microbiology · 2026Article
- Integrated genomic analysis ofFrontiers in microbiology · 2026Article
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Authors and funding
6 authors.
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Abstract
Stenotrophomonas maltophilia (S. maltophilia) has emerged as an important nosocomial pathogen and causes life-threatening infections among the vulnerable, and occasionally in immunocompetent individuals. We examined the mechanisms of multidrug resistance in S. maltophilia isolated from sick and healthy individuals in Nigeria. Susceptibility testing and genome sequencing revealed multidrug resistance and carriage of multiple antimicrobial resistance genes in all isolates. Genes encoding resistance to fluoroquinolones, beta-lactams, aminoglycosides, chloramphenicol, sulphonamide and trimethoprim including oqxB, bla1_3, aph(3), cmlB1, sul and dfrA, variants were found in all the isolates. Genome analysis revealed multiple plasmids were present in the strains including ColBS512, ColMG828, and IncR plasmids. Resistance to multiple drugs compromises the treatment option for S. maltophilia limiting a potential treatment option that can cause serious nosocomial infections.
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