Evidence map›Paper›PMID 40190352›Full record

ArticleBrain communications2025

Association of blood-based glial fibrillary acidic protein level with depression and suicidal ideation following traumatic brain injury with Glasgow Coma Scale score 13 to 15: a TRACK-TBI study.

Shawn R Eagle, Raquel C Gardner, Sonia Jain, Xiaoying Sun, Ava Puccio, David Brent, Lindsay D Nelson, Michael A McCrea, Joseph T Giacino, David O Okonkwo and 4 more

Abstract read
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In one paragraph

Article in Brain communications, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

14 authors.

Shawn R EagleDepartment of Neurological Surgery, University of Pittsburgh, Pittsburgh, PA 15261, USA.ORCID https://orcid.org/0000-0001-6767-1042
Raquel C GardnerDepartment of Epidemiology, Sheba Medical Center, Ramat Gan 52621, Israel.
Sonia JainDepartment of Family Medicine and Public Health, University of California San Diego, La Jolla, CA 92093, USA.
Xiaoying SunDepartment of Family Medicine and Public Health, University of California San Diego, La Jolla, CA 92093, USA.
Ava PuccioDepartment of Neurological Surgery, University of Pittsburgh, Pittsburgh, PA 15261, USA.
David BrentDepartment of Neurological Surgery, University of Pittsburgh, Pittsburgh, PA 15261, USA.
Lindsay D NelsonDepartment of Neurosurgery, Medical College of Wisconsin, Milwaukee, WI 53226, USA.
Michael A McCreaDepartment of Neurosurgery, Medical College of Wisconsin, Milwaukee, WI 53226, USA.
Joseph T GiacinoDepartment of Physical Medicine and Rehabilitation, Harvard University, Cambridge, MA 02129, USA.
David O OkonkwoDepartment of Neurological Surgery, University of Pittsburgh, Pittsburgh, PA 15261, USA.
John K YueDepartment of Neurological Surgery, University of California San Francisco, San Francisco, CA 94143, USA.ORCID https://orcid.org/0000-0001-9694-7722
Geoffrey T ManleyDepartment of Neurological Surgery, University of California San Francisco, San Francisco, CA 94143, USA.
Murray B SteinDepartment of Family Medicine and Public Health, University of California San Diego, La Jolla, CA 92093, USA.
TRACK-TBI Investigators

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Blood-based glial fibrillary acidic protein (GFAP) level within 24 h of traumatic brain injury (TBI) has been inversely associated with post-traumatic stress disorder at 6 months in the Transforming Research and Clinical Knowledge in Traumatic Brain Injury (TRACK-TBI) study. We sought to assess the relationship between day-of-injury GFAP and cumulative prevalence (CI) of depression or suicidal ideation in the first year after injury among patients presenting with Glasgow Coma Scale 13-15 who participated in Transforming Research and Clinical Knowledge in Traumatic Brain Injury (

Indexed as

blood biomarkerGFAPsuicidal ideationtraumatic brain injury

Identifiers

PMID40190352
PMCPMC11968334

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.