Evidence map›Paper›PMID 40190301›Full record

ArticleArchives of medical science : AMS2025

Risk factors of incomplete endothelialization after left atrial appendage occlusion in patients with atrial fibrillation.

Jia-Min Chen, Zhong-Bao Ruan, Ge-Cai Chen, Jun-Guo Zhu, Yin Ren, Li Zhu

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Article in Archives of medical science : AMS, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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5 · Who and what money

Authors and funding

6 authors.

Jia-Min ChenDepartment of Cardiology, the Affiliated Taizhou People's Hospital of Nanjing Medical University, Taizhou School of Clinical Medicine, Nanjing Medical University, Taizhou, China.
Zhong-Bao RuanDepartment of Cardiology, the Affiliated Taizhou People's Hospital of Nanjing Medical University, Taizhou School of Clinical Medicine, Nanjing Medical University, Taizhou, China.
Ge-Cai ChenDepartment of Cardiology, the Affiliated Taizhou People's Hospital of Nanjing Medical University, Taizhou School of Clinical Medicine, Nanjing Medical University, Taizhou, China.
Jun-Guo ZhuDepartment of Cardiology, the Affiliated Taizhou People's Hospital of Nanjing Medical University, Taizhou School of Clinical Medicine, Nanjing Medical University, Taizhou, China.
Yin RenDepartment of Cardiology, the Affiliated Taizhou People's Hospital of Nanjing Medical University, Taizhou School of Clinical Medicine, Nanjing Medical University, Taizhou, China.
Li ZhuDepartment of Cardiology, the Affiliated Taizhou People's Hospital of Nanjing Medical University, Taizhou School of Clinical Medicine, Nanjing Medical University, Taizhou, China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Introduction: We aimed to investigate the risk factors of incomplete device endothelialization (IDE) following left atrial appendage occlusion (LAAO) and provide a nomogram model for predicting the risks of IDE in patients with atrial fibrillation (AF). Material and methods: A total of 145 patients with AF who underwent LAAO were included. The endothelialization of the occluder was assessed by computed tomography angiography (CTA) at 3 months after LAAO. Logistic regression analysis was used to explore the risk factors of IDE after LAAO. A nomogram model was constructed to predict the risks of IDE. Results: 53 cases with complete endothelialization (CDE group) and 92 cases with IDE (IDE group) were detected at 3 months after LAAO. There was a significant difference in mitral regurgitation (MR) (37.7% vs. 55.4%, Conclusions: MR, higher serum urea level, LAA diameter and large occluder size may contribute to IDE after LAAO. The nomogram model based on MR, LAA diameter, occluder size and serum urea can be used to predict the IDE after LAAO.

Indexed as

atrial fibrillationendothelializationleft atrial appendage occlusionocclude

Identifiers

PMID40190301
PMCPMC11969505

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.