Evidence map›Paper›PMID 40190197›Full record

ArticleBiomacromolecules2025

Synthesis and Characterization of Free Radical Scavenging Dendrimer Nanogels via Cross-Linking Reaction-Enabled Flash Nanoprecipitation.

Lin Qi, Da Huang, Huari Kou, Anna Chernatynskaya, Nuran Ercal, Hu Yang

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Biomacromolecules, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Article
  2. Article
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Lin QiLinda and Bipin Doshi Department of Chemical and Biochemical Engineering, Missouri University of Science and Technology, Rolla, Missouri 65409, United States.
Da HuangCollege of Biological Science and Engineering, Fuzhou University, Fuzhou, Fujian 350108, China.ORCID 0000-0003-3621-5233
Huari KouLinda and Bipin Doshi Department of Chemical and Biochemical Engineering, Missouri University of Science and Technology, Rolla, Missouri 65409, United States.
Anna ChernatynskayaLinda and Bipin Doshi Department of Chemical and Biochemical Engineering, Missouri University of Science and Technology, Rolla, Missouri 65409, United States.
Nuran ErcalDepartment of Chemistry, Missouri University of Science and Technology, Rolla, Missouri 65409, United States.
Hu YangLinda and Bipin Doshi Department of Chemical and Biochemical Engineering, Missouri University of Science and Technology, Rolla, Missouri 65409, United States.ORCID 0000-0003-3030-004X

Funding

Modulating Macrophage Function in Atherosclerosis by Functionalized NanoparticlesR01HL140684 · NHLBI · VIRGINIA COMMONWEALTH UNIVERSITY · PI GHOSH, SIDDHARTHA S, YANG, HU · 2018 to 2021
$2.5M
Modulating aqueous humor outflow with engineered nanoparticles for glaucomaR01EY035088 · NEI · MISSOURI UNIVERSITY OF SCIENCE & TECHNOLOGY · PI Xiaorong Liu, Hu Yang · 2023 to 2026
$2.0M
NEI NIH HHS R01 EY035088NHLBI NIH HHS R01 HL140684
6 · The paper itself

Abstract

This work reports the development and evaluation of dendrimer-based nanogels based on polyamidoamine (PAMAM) dendrimer generation 5, engineered to act as a carrier with reactive oxygen species (ROS)-scavenging capabilities. We developed a cross-linking reaction-enabled flash nanoprecipitation method in which the cross-linking reaction occurs during the flash nanoprecipitation process to form a cross-linked nanostructure. Using this approach, an

Indexed as

DendrimersFree Radical ScavengersPolyethylene GlycolsPolyethyleneimineAnimalsCross-Linking ReagentsHumansMiceNanogelsReactive Oxygen SpeciesCross-Linking ReagentsDendrimersFree Radical ScavengersNanogelsPAMAM StarburstPolyethylene GlycolsPolyethyleneimineReactive Oxygen Species

Identifiers

PMID40190197
PMCPMC12633722

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.