Evidence map›Paper›PMID 40189941›Full record

ArticleNursing in critical care2025

Extending the interval for changing flushing solutions for central venous and arterial line systems in the intensive care unit: An evidence-based quality improvement project.

Junel Padigos, Lauren Murray, Olivia Bredhauer, Jenny Jaspers, Sue Bethune

Abstract read
In one paragraph

Article in Nursing in critical care, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Junel PadigosSchool of Public Health, The University of Queensland, Herston, Queensland, Australia.ORCID https://orcid.org/0000-0002-0937-838X
Lauren MurrayIntensive Care Unit, Sunshine Coast Hospital and Health Service, Birtinya, Queensland, Australia.ORCID https://orcid.org/0000-0002-7567-1525
Olivia BredhauerIntensive Care Unit, Sunshine Coast Hospital and Health Service, Birtinya, Queensland, Australia.ORCID https://orcid.org/0009-0002-3956-1940
Jenny JaspersIntensive Care Unit, Sunshine Coast Hospital and Health Service, Birtinya, Queensland, Australia.ORCID https://orcid.org/0009-0001-7933-7620
Sue BethuneSCHI Library, Sunshine Coast Hospital and Health Service, Birtinya, Queensland, Australia.ORCID https://orcid.org/0000-0002-9494-3709

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundCentral venous lines (CVLs) and arterial lines (ALs) are commonly used for patients in the intensive care units (ICUs) to facilitate the administration of medications and haemodynamic monitoring. In an ICU in Queensland, Australia (AU), saline (sodium chloride 0.9%) flush bags used for these lines were routinely changed every 24 h following organizational policy that all intravenous fluid bags are to be changed within a 24-h period.

aimThis quality improvement (QI) project aimed to evaluate current practice guided by the Plan-Do-Study-Act (PDSA) model of QI and implementation science. Benchmarking practices with other ICUs was conducted. STUDY

designA narrative literature review focused on evaluating the safe interval for changing flush solutions every 24 h was performed using EBSCO Medline, CINAHL, Cochrane Library, Embase and Google Scholar databases for citations up to November 2022. Bloodstream infection rates attributed to CVLs and/or ALs were monitored. Economic analysis was performed. End-user feedback was sought. A change of practice was implemented for a 1-year study period (March 2023 - March 2024) to extend dwell times of flushing solutions for CVLs and ALs from every 24 h to every 96 h.

resultsOne-year post-implementation, no bloodstream infections were linked to CVLs or ALs. A simplified economic analysis was performed based on costs of 0.9% sodium chloride 500-mL fluid bags, which revealed that changing the fluid bags once every 96 h resulted in a per patient saving of AU$3.21 for any individual AL or CVL and up to AU$6.42 per patient where both an AL and CVL are in situ, based on fluid bag cost at AU$1.07 per bag. This saving excludes potential savings from reduced nursing time, infection-related costs and recycling costs.

conclusionA sustainable practice change based on evidence was implemented in the local ICU. The use of the PDSA model of the QI process and the principles of implementation science strengthened the buy-in and implementation of the project. RELEVANCE TO CLINICAL PRACTICE: This practice change was examined through lenses of evidence-based practice, environmental sustainability (minimizing environmental footprint by limiting plastic bag usage), patient safety, cost minimization, and reduced nursing workload.

Indexed as

Catheterization, Central VenousIntensive Care UnitsQuality ImprovementCatheter-Related InfectionsHumansQueenslandTime Factorsarterial linecentral venous lineevidence‐based practicefluid stewardshipflush bag change

Identifiers

PMID40189941
PMCPMC11973469

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LicenceCC BY-NC-ND
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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.