Evidence map›Paper›PMID 40189829›Full record

ArticleAlzheimer's & dementia : the journal of the Alzheimer's Association2025

Neighborhood disadvantage and the incidence of dementia in US Black women.

Patricia F Coogan, Lauren Delp, Jacqueline N Hicks, Tanisha G Hill-Jarrett, Kasim Ortiz, Bryan D James, Zinzi Bailey, Lisa L Barnes, Lynn Rosenberg

Abstract read
In one paragraph

Article in Alzheimer's & dementia : the journal of the Alzheimer's Association, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

10 citing papers in PubMed.

  1. Multimorbidity, Polypharmacy, and Neighborhood Disadvantage as Determinants of Cognitive Performance in the ARCHES Cohort.Journal of applied gerontology : the official journal of the Southern Gerontological Society · 2026
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  10. Neighborhood disadvantage and the incidence of dementia in US Black women.Alzheimer's & dementia : the journal of the Alzheimer's Association · 2025
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Patricia F CooganSlone Epidemiology Center at Boston University, Boston, Massachusetts, USA.
Lauren DelpSlone Epidemiology Center at Boston University, Boston, Massachusetts, USA.
Jacqueline N HicksDepartment of Biostatistics, Boston University School of Public Health, Boston, Massachusetts, USA.
Tanisha G Hill-JarrettMemory and Aging Center, Department of Neurology, University of California San Francisco, San Francisco, California, USA.
Kasim OrtizDepartment of Health Management and Policy, Drexel Dornsife School of Public Health, Philadelphia, Pennsylvania, USA.
Bryan D JamesRush Alzheimer's Disease Center, Chicago, Illinois, USA.
Zinzi BaileyDivision of Epidemiology & Community Health, University of Minnesota, Minneapolis, Minnesota, USA.
Lisa L BarnesRush Alzheimer's Disease Center, Chicago, Illinois, USA.
Lynn RosenbergSlone Epidemiology Center at Boston University, Boston, Massachusetts, USA.

Funding

A Follow-up Study for Causes of Cancer in Black WomenU01CA164974 · NCI · BOSTON UNIVERSITY MEDICAL CAMPUS · PI Kimberly A. Bertrand, Yvette C Cozier · 2017 to 2026
$24.0M
The Influence of Structural Racism on Incidence of Alzheimer's Disease and Related Dementias (ADRD) in Black womenR01AG077948 · NIA · BOSTON UNIVERSITY MEDICAL CAMPUS · PI Astrid M Suchy-Dicey · 2022 to 2026
$3.7M
Predictors and consequences of the timing and accuracy of clinical dementia diagnosisR01AG072559 · NIA · RUSH UNIVERSITY MEDICAL CENTER · PI Bryan David James · 2022 to 2026
$2.9M
Structural Gendered RacismK23AG084871 · NIA · UNIVERSITY OF CALIFORNIA, SAN FRANCISCO · PI Tanisha G Hill-Jarrett · 2024 to 2026
$593k
NCI NIH HHS U01 CA164974NCI NIH HHS U01CA164974NIA NIH HHS K23 AG084871NIA NIH HHS R01 AG072559NIA NIH HHS R01 AG077948NIH HHS R01AG072559NIH HHS R01AG077948
6 · The paper itself

Abstract

introductionWe investigated the association of neighborhood disadvantage with the incidence of Alzheimer's disease and related dementias (ADRD) in the longitudinal Black Women's Health Study (BWHS).

methodsThe study included 10,915 BWHS participants enrolled in Medicare for at least 1 year from 2012 to 2020. The Area Deprivation Index (ADI) was assigned to participant residential block groups over follow-up. ADRD cases were identified from Medicare files.

resultsAge- and education-adjusted hazard ratios (HRs) for ADRD increased as neighborhood disadvantage increased, to 1.42 (95% confidence interval [CI] 1.06-1.91) in the most disadvantaged quintile compared to the least disadvantaged quintile, with a significant linear trend (p = 0.012). Associations remained, although somewhat attenuated, when individual income was controlled. DISCUSSION: The present study adds to the evidence showing an association between living in a disadvantaged neighborhood and poorer brain health. The area-level association of deprivation with ADRD was in part explained by individual differences in socioeconomic status (SES). HIGHLIGHTS: The study assessed neighborhood deprivation in the largest cohort of US Black women. Cases of dementia were ascertained from Medicare claims files over 9 years of follow-up. Higher levels of area deprivation were associated with higher dementia risk.

Indexed as

Black or African AmericanDementiaNeighborhood CharacteristicsResidence CharacteristicsAgedAged, 80 and overFemaleHumansIncidenceLongitudinal StudiesMedicareRisk FactorsSocioeconomic FactorsUnited StatesAfrican American womenArea Deprivation Indexdementialongitudinal studyneighborhood disadvantage

Identifiers

PMID40189829
PMCPMC11973127

What OpenQuestion holds

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LicenceCC BY-NC-ND
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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.