Evidence map›Paper›PMID 40189746›Full record

ArticlePaediatric and perinatal epidemiology2025

Reducing Inequalities in Timing of Antenatal Care Initiation: A Hypothetical Intervention in the Generation R Study.

Clair A Enthoven, Jeremy A Labrecque, Hanan El Marroun, Nicole Lucassen, Dionne V Gootjes, Eefje van Vliet, Hilmar H Bijma, Pauline W Jansen

Abstract read
In one paragraph

Article in Paediatric and perinatal epidemiology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Clair A EnthovenDepartment of Child and Adolescent Psychiatry/Psychology, Erasmus University Medical Center, Rotterdam, the Netherlands.ORCID https://orcid.org/0000-0003-0812-8765
Jeremy A LabrecqueDepartment of Epidemiology, Erasmus University Medical Center, Rotterdam, the Netherlands.ORCID https://orcid.org/0000-0002-1028-2158
Hanan El MarrounDepartment of Child and Adolescent Psychiatry/Psychology, Erasmus University Medical Center, Rotterdam, the Netherlands.ORCID https://orcid.org/0000-0002-9763-5015
Nicole LucassenDepartment of Psychology, Education and Child Studies, Erasmus School of Social and Behavioural Sciences, Erasmus University, Rotterdam, the Netherlands.ORCID https://orcid.org/0000-0002-3432-0382
Dionne V GootjesThe Generation R Study Group, Erasmus University Medical Center, Rotterdam, the Netherlands.ORCID https://orcid.org/0000-0002-9382-9031
Eefje van VlietDepartment of Obstetrics and Gynaecology, Division of Obstetrics and Fetal Medicine, Erasmus MC Sophia, Rotterdam, the Netherlands.
Hilmar H BijmaDepartment of Obstetrics and Gynaecology, Division of Obstetrics and Fetal Medicine, Erasmus MC Sophia, Rotterdam, the Netherlands.ORCID https://orcid.org/0000-0002-5800-8051
Pauline W JansenDepartment of Child and Adolescent Psychiatry/Psychology, Erasmus University Medical Center, Rotterdam, the Netherlands.ORCID https://orcid.org/0000-0001-7747-5803

Funding

GGD-GHORHorizon 2020 Framework ProgrammeNederlandse Organisatie voor Wetenschappelijk OnderzoekStichting Volksbond RotterdamVital Cities and CitizensZonMw
6 · The paper itself

Abstract

backgroundMuch research has focused on identifying predictors of late antenatal care initiation. Many of these predictors (e.g., young age, migration background, socioeconomic position) are impossible to modify, illustrating the need to explore other interventions.

objectivesThis study aims to investigate inequalities in antenatal care initiation and assess whether early pregnancy recognition may reduce these inequalities.

methodsData from Generation R were used (N = 4196), a population-based birth cohort study in Rotterdam, The Netherlands. The association of gestational age at pregnancy recognition with the timing of antenatal care initiation and associations of individual and socioeconomic factors with the timing of antenatal care initiation were assessed using linear regression analyses. G-methods were used to estimate the reduction of the inequalities in antenatal care initiation if everyone would have recognised the pregnancy within 6 weeks.

resultsParticipants who recognised their pregnancy within 6 weeks (81.7%) had their first antenatal care visit 1.3 weeks (95% confidence interval [CI] -1.6, -0.9) earlier than those who recognised their pregnancy after 6 weeks. All individual and socioeconomic factors were associated with the timing of antenatal care initiation. Modelling a scenario where pregnancy recognition occurred within 6 weeks reduced inequalities in antenatal care initiation timing across several groups: age < 20 versus 30-35 (-0.4 weeks, 95% CI -0.7, -0.2), first-generation migrants versus no migration (-0.1 weeks, 95% CI -0.2, 0.0), unplanned/ambivalent versus planned pregnancies (-0.4 weeks, 95% CI -0.6, -0.2), lower versus higher educational attainment (-0.1 weeks, 95% CI -0.2, 0.0), unemployed versus employed (-0.1 weeks, 95% CI -0.2, 0.0), low versus high household income (-0.1 weeks, 95% CI -0.3, 0.0), renters versus homeowners (-0.1 weeks, 95% CI -0.2, 0.0), and high versus low neighbourhood deprivation (-0.1 weeks, 95% CI -0.2, -0.1).

conclusionsEarly recognition of pregnancy may help reduce the impact of socio-economic inequalities in the timely initiation of antenatal care.

Indexed as

Healthcare DisparitiesPatient Acceptance of Health CarePrenatal CareAdultFemaleGestational AgeHumansNetherlandsPregnancySocioeconomic FactorsTime FactorsYoung Adultantenatal carefamily planninghypothetical interventioninequalitiespregnancy recognition

Identifiers

PMID40189746
PMCPMC12391855

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.