Evidence map›Paper›PMID 40189696›Full record

ArticleScientific reports2025

Loneliness and repetitive negative thinking mediate the link between social health and cardiac distress in heart disease patients.

Hamid Sharif-Nia, Alun C Jackson, Safoura Salehi, Fateme Miraghai, Seyed Hamzeh Hosseini

Abstract read
In one paragraph

Article in Scientific reports, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

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3 · Its place in the literature

Who cites it

10 citing papers in PubMed.

  1. Article
  2. Article
  3. Review
  4. Article
  5. [Psychocardiology].Der Nervenarzt · 2026
    Review
  6. Article
  7. Article
  8. Article
  9. Article
  10. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Hamid Sharif-NiaPsychosomatic Research Center, Mazandaran University of Medical Sciences, Sari, Iran.
Alun C JacksonCentre on Behavioral Health, Hong Kong University, Pokfulam, Hong Kong, People's Republic of China.
Safoura SalehiImam Khomeini Hospital, Mazandaran University of Medical Sciences, Sari, Iran.
Fateme MiraghaiStudent Research Committee, Mazandaran University of Medical Sciences, Sari, Iran. fateme.miraghai76@gmail.com.
Seyed Hamzeh HosseiniPsychosomatic Research Center, Mazandaran University of Medical Sciences, Sari, Iran.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Cardiovascular diseases are the leading cause of mortality worldwide, contributing to one-third of global deaths. Beyond physical health, heart disease is associated with cardiac distress, an emotional response that can negatively impact recovery and well-being. Understanding the psychological and social mechanisms underlying cardiac distress is crucial for improving patient outcomes. This study examines how social health (social support and social isolation) influences cardiac distress, with loneliness and repetitive negative thinking as mediators. To evaluate a theoretical model linking social health to cardiac distress, mediated by loneliness and repetitive negative thinking in patients with heart disease. A cross-sectional, correlational study was conducted in 2024 with 400 cardiac patients from two hospitals and one private clinic in Amol, Iran. Participants completed validated questionnaires assessing cardiac distress, social support, social isolation, loneliness, and repetitive negative thinking. Structural equation modeling was used for data analysis. Social isolation (r = 0.47, p < 0.001) and repetitive negative thinking (r = 0.50, p < 0.001) were significantly associated with greater cardiac distress. Social support negatively predicted both loneliness (β = - 0.32, p < 0.001) and cardiac distress (β = - 0.25, p < 0.01). Indirect effects showed that social support reduced cardiac distress by decreasing loneliness and repetitive negative thinking (β = - 0.23, p < 0.01), while social isolation increased cardiac distress through its influence on loneliness and repetitive negative thinking (β = 0.18, p = 0.05). The model explained 47.4% of the variance in cardiac distress. These findings highlight the importance of social health in managing cardiac distress among heart disease patients. Strengthening social support may alleviate loneliness and reduce repetitive negative thinking, ultimately improving emotional well-being and health outcomes. Future research should explore targeted interventions addressing these psychosocial factors to effectively reduce cardiac distress.

Indexed as

Heart DiseasesLonelinessStress, PsychologicalThinkingAdultAgedCross-Sectional StudiesFemaleHumansIranMaleMiddle AgedSocial IsolationSocial SupportSurveys and QuestionnairesCardiac distressCardiovascular diseasesLonelinessRepetitive negative thinkingSocial isolationSocial support

Identifiers

PMID40189696
PMCPMC11973143

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.