ReviewNature communications2025
Life on the dry side: a roadmap to understanding desiccation tolerance and accelerating translational applications.
Review in Nature communications, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 26 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
26 citing papers in PubMed.
- Article
- Scientists' warning on the global destruction of rock outcrop ecosystems.Conservation biology : the journal of the Society for Conservation Biology · 2026Article
- Desiccation tolerance as a driver of environmental persistence and transmission in nosocomial bacterial pathogens.Infection and immunity · 2026Review
- Desiccation tolerance mechanisms in the green lineage and beyond.The New phytologist · 2026Review
- Cryopreservation and other preservation approaches for animal models workshop session I: Invertebrate models in biomedical research.Cryobiology · 2026Article
- Dehydration-driven organization of metabolites into NaDES-like assemblies in orthodox seeds.The New phytologist · 2026Article
- An IDA peptide from Boea hygrometrica enhances desiccation tolerance but lacks activity in Arabidopsis.Planta · 2026Article
- Contrasting Photochemical Stability and Oxidative Injury Shape Drought Responses in Ferns and Mosses.Plants (Basel, Switzerland) · 2026Article
- Review
- SeedMatExplorer: the transcriptome atlas of Arabidopsis seed maturation.BMC plant biology · 2026Article
- "Let's Dry up and Survive Together": Is Anhydrobiosis in TwoInternational journal of molecular sciences · 2026Article
- The Biosynthesis and Functions of Flavonoids: Recent Advances From Studies Across Land Plant Diversity.Journal of the Royal Society of New Zealand · 2026Review
- Hyperactive ice-binding proteins stabilize cell membranes and improve resistance to dehydration stress in Caenorhabditis elegans.FEBS open bio · 2026Article
- Evidence that local viscosity and NOX-dependent ROS increases render the tardigrade H. exemplaris resilient to extreme physical force.bioRxiv : the preprint server for biology · 2026Article
- Rapid desiccation and on-disc rehydration of extracellular vesicles for non-cryogenic preservation.Lab on a chip · 2026Article
- Biofilms reshape soil-water dynamics with enhanced vapor adsorption and hysteresis reversal under dry conditions.NPJ biofilms and microbiomes · 2026Article
- Shaped by context: Evolutionary trajectories of desiccation tolerance in land plants.American journal of botany · 2026Review
- Aging and longevity in decades-old genebanked seeds from U.S. endangered plant species: Assessments using survival and RNA integrity assays.American journal of botany · 2026Article
- Drying parameters and aging modulate protective properties of vitrified trehalose.bioRxiv : the preprint server for biology · 2026Article
- Mechanisms of viability loss in dehydratedFrontiers in microbiology · 2026Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
39 authors.
Funding
Abstract
To thrive in extreme conditions, organisms have evolved a diverse arsenal of adaptations that confer resilience. These species, their traits, and the mechanisms underlying them comprise a valuable resource that can be mined for numerous conceptual insights and applied objectives. One of the most dramatic adaptations to water limitation is desiccation tolerance. Understanding the mechanisms underlying desiccation tolerance has important potential implications for medicine, biotechnology, agriculture, and conservation. However, progress has been hindered by a lack of standardization across sub-disciplines, complicating the integration of data and slowing the translation of basic discoveries into practical applications. Here, we synthesize current knowledge on desiccation tolerance across evolutionary, ecological, physiological, and cellular scales to provide a roadmap for advancing desiccation tolerance research. We also address critical gaps and technical roadblocks, highlighting the need for standardized experimental practices, improved taxonomic sampling, and the development of new tools for studying biology in a dry state. We hope that this perspective can serve as a roadmap to accelerating research breakthroughs and unlocking the potential of desiccation tolerance to address global challenges related to climate change, food security, and health.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.