ArticleBMC plant biology2025
The key metabolic pathway of roots and leaves responses in Arachis hypogaea under Al toxicity stress.
Article in BMC plant biology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
2 citing papers in PubMed.
- Genome-wide identification and gene expression analysis of Formin homology 2 (FH2) genes in peanut.BMC plant biology · 2026Article
- Genome-wide identification and gene expression analysis of AhNHXs in peanut.BMC plant biology · 2026Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
7 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundAluminum (Al) toxicity inhibits plant growth and alters gene expression and metabolite profiles. However, the molecular mechanisms underlying the effects of Al toxicity on peanut plants remain unclear. Transcriptome and metabolome analyses were conducted to investigate the responses of peanut leaves and roots to Al toxicity.
resultsAl toxicity significantly inhibited peanut growth, disrupted antioxidant enzyme systems in roots and leaves, and impaired nutrient absorption. Under Al toxicity stress, the content of indole-3-acetic acid-aspartate (IAA-Asp) decreased by 23.94% in leaves but increased by 12.91% in roots. Methyl jasmonate (MeJA) levels in leaves increased dramatically by 2642.86%. Methyl salicylate (MeSA) content in leaves and roots increased significantly by 140.00% and 472.22%, respectively. Conversely, isopentenyl adenosine (IPA) content decreased by 78.95% in leaves and 20.66% in roots. Transcriptome analysis identified 5831 differentially expressed genes (DEGs) in leaves and 6405 DEGs in roots, whereas metabolomics analysis revealed 210 differentially accumulated metabolites (DAMs) in leaves and 240 DAMs in roots. Under Al toxicity stress, both leaves and roots were significantly enriched in the "linoleic acid metabolism" pathway. Genes such as lipoxygenase LOX1-5 and LOX2S were differentially expressed, and metabolites, including linoleic acid and its oxidized derivatives, were differentially accumulated, mitigating oxidative stress.
conclusionsThis study elaborates on the potential complex physiological and molecular mechanisms of peanuts under aluminum toxicity stress, and highlights the importance of linoleic acid metabolism in coping with aluminum toxicity. These findings enhance our understanding of the impact of aluminum toxicity on peanut development and the response of key metabolic pathways, providing potential molecular targets for genetic engineering to improve crop resistance to aluminum stress.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.