Evidence map›Paper›PMID 40189179›Full record

ReviewSeminars in thoracic and cardiovascular surgery2025

Arrhythmic Mitral Valve Prolapse: Pathophysiology, Diagnostics, and Management Strategies.

Jagdip Kang, Antonia van Kampen, Maja-Theresa Dieterlen, Ricardo Spampinato, Thoralf Sundt, Serguei Melnitchouk, Robert A Levine, Michael A Borger

Abstract readReview
PubMed Full text at PMC Publisher
In one paragraph

Review in Seminars in thoracic and cardiovascular surgery, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Jagdip KangUniversity Department of Cardiac Surgery, Heart Center Leipzig, Leipzig, Germany; Division of Cardiac Surgery, Massachusetts General Hospital, Harvard Medical School, Boston, Massachusetts.
Antonia van KampenUniversity Department of Cardiac Surgery, Heart Center Leipzig, Leipzig, Germany.
Maja-Theresa DieterlenUniversity Department of Cardiac Surgery, Heart Center Leipzig, Leipzig, Germany.
Ricardo SpampinatoUniversity Department of Cardiac Surgery, Heart Center Leipzig, Leipzig, Germany.
Thoralf SundtDivision of Cardiac Surgery, Massachusetts General Hospital, Harvard Medical School, Boston, Massachusetts.
Serguei MelnitchoukDivision of Cardiac Surgery, Massachusetts General Hospital, Harvard Medical School, Boston, Massachusetts.
Robert A LevineCardiac Ultrasound Laboratory, Harvard Medical School, Massachusetts General Hospital, Boston, Massachusetts.
Michael A BorgerUniversity Department of Cardiac Surgery, Heart Center Leipzig, Leipzig, Germany. Electronic address: Michael.borger@helios-gesundheit.de.

Funding

Mechanism of Myocardial Fibrosis Induced by Mitral Valve ProlapseR01HL173930 · NHLBI · MASSACHUSETTS GENERAL HOSPITAL · PI JUDY W HUNG, Serguei MELNITCHOUK · 2024 to 2026
$5.4M
Structure/Function Determinants of Platelet Granule SecretionR01HL119393 · NHLBI · UNIV OF ARKANSAS FOR MED SCIS · PI STORRIE, BRIAN · 2013 to 2016
$1.4M
NHLBI NIH HHS R01 HL119393NHLBI NIH HHS R01 HL173930
6 · The paper itself

Abstract

Mitral valve prolapse (MVP) is a common disease in which ventricular arrhythmias/sudden cardiac death can be the first symptom of presentation. This review article explores the current understanding of underlying pathological mechanisms leading to an increased risk for ventricular arrhythmias in the setting of MVP and elaborates on the current evidence regarding the diagnosis and management of the disease.

Indexed as

Arrhythmias, CardiacDeath, Sudden, CardiacMitral ValveMitral Valve ProlapseHeart RateHumansPredictive Value of TestsRisk FactorsTreatment Outcomearrhythmic mitral valve prolapsemitral valvemitral valve prolapsesudden cardiac deathventricular arrhythmiaventricular fibrosis

Identifiers

PMID40189179
PMCPMC12212166

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.