Evidence map›Paper›PMID 40189085›Full record

ArticleEnvironmental pollution (Barking, Essex : 1987)2025

Exposure to polyoxyethylene tallow amines (POEAs), glyphosate co-formulation surfactants, in a US pregnant population and their potential endocrine disrupting effects.

Bushra Amreen, Corina Lesseur, Ravikumar Jagani, Shirisha Yelamanchili, Emily S Barrett, Ruby H N Nguyen, Sheela Sathyanarayana, Shanna H Swan, Syam S Andra, Jia Chen

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Environmental pollution (Barking, Essex : 1987), 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed.

  1. Article
  2. Article
  3. Review
  4. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Bushra AmreenDepartment of Environmental Medicine, Icahn School of Medicine at Mount Sinai, New York, NY, 10029, USA.
Corina LesseurDepartment of Environmental Medicine, Icahn School of Medicine at Mount Sinai, New York, NY, 10029, USA.
Ravikumar JaganiDepartment of Environmental Medicine, Icahn School of Medicine at Mount Sinai, New York, NY, 10029, USA.
Shirisha YelamanchiliDepartment of Environmental Medicine, Icahn School of Medicine at Mount Sinai, New York, NY, 10029, USA.
Emily S BarrettDepartment of Biostatistics and Epidemiology, Rutgers School of Public Health, Piscataway, NJ, 08854, USA.
Ruby H N NguyenDepartment of Epidemiology and Community Health, University of Minnesota, Minneapolis, MN, 55454, USA.
Sheela SathyanarayanaDepartment of Pediatrics, University of Washington and Seattle Children's Research Institute, Seattle, WA, USA.
Shanna H SwanDepartment of Environmental Medicine, Icahn School of Medicine at Mount Sinai, New York, NY, 10029, USA.
Syam S AndraDepartment of Environmental Medicine, Icahn School of Medicine at Mount Sinai, New York, NY, 10029, USA.
Jia ChenDepartment of Environmental Medicine, Icahn School of Medicine at Mount Sinai, New York, NY, 10029, USA. Electronic address: jia.chen@mssm.edu.

Funding

XENOBIOTIC BIOTRANSFORMATION AND DISPOSITIONP30ES007033 · NIEHS · UNIVERSITY OF WASHINGTON · PI Sheela Sathyanarayana · 1995 to 2026
$42.5M
Untargeted Analysis ResourceU2CES026561 · NIEHS · ICAHN SCHOOL OF MEDICINE AT MOUNT SINAI · PI WRIGHT, ROBERT O · 2015 to 2025
$24.5M
The Mount Sinai Transdisciplinary Center on Early Environmental ExposuresP30ES023515 · NIEHS · ICAHN SCHOOL OF MEDICINE AT MOUNT SINAI · PI Manish Arora · 2014 to 2026
$21.3M
The Infant Development and the Environmental Study (TIDES)R01ES016863 · NIEHS · UNIVERSITY OF ROCHESTER · PI SWAN, SHANNA H · 2009 to 2014
$4.0M
Phthalate and stressful life event exposures and pregnancy outcomes: The role of oxidative stressZIAES103313 · NIEHS · NATIONAL INSTITUTE OF ENVIRONMENTAL HEALTH SCIENCES · PI FERGUSON, KELLY · 2016 to 2022
$1.9M
Intramural NIH HHS ZIA ES103313NIEHS NIH HHS P30 ES007033NIEHS NIH HHS P30 ES023515NIEHS NIH HHS R01 ES016863NIEHS NIH HHS U2C ES026561
6 · The paper itself

Abstract

Emerging but inconsistent evidence suggests that glyphosate (GLY)-based herbicides (GBHs) are more toxic than the active ingredient, GLY alone. Polyoxyethylene tallow amines (POEAs) are surfactants most widely used in GBH formulations, making up to 5-15 % by weight. However, neither POEA exposure nor their toxicity has been well studied in the general population. This study leverages second trimester urine samples collected from 86 pregnant participants of a multi-center, US-based pregnancy cohort. We measured three POEA homologs, i.e., C

Indexed as

AminesEndocrine DisruptorsGlycineHerbicidesMaternal ExposurePolyethylene GlycolsSurface-Active AgentsAdultFemaleGlyphosateHumansMalePregnancyUnited StatesYoung AdultAminesEndocrine DisruptorsGlycineGlyphosateHerbicidesPolyethylene GlycolspolyoxyethyleneamineSurface-Active AgentsAno-genital distanceEndocrine-disrupting chemicalsGlyphosateGlyphosate-based herbicidesPOEAPolyethoxylated tallow aminesSurfactants

Identifiers

PMID40189085
PMCPMC12091687

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.