Evidence map›Paper›PMID 40188881›Full record

ArticlePreventive medicine2025

Factors associated with human papillomavirus (HPV) patient-clinician communication and HPV vaccine uptake among adults in the United States.

Heather N Owens, Naomi C Brownstein, Junmin Whiting, Mariana Arevalo, Monica L Kasting, Susan T Vadaparampil, Katharine J Head, Shannon M Christy

Abstract read
In one paragraph

Article in Preventive medicine, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Heather N OwensDepartment of Health Outcomes and Behavior, Moffitt Cancer Center, Tampa, FL, USA.
Naomi C BrownsteinDepartment of Public Health Sciences, Medical University of South Carolina, Charleston, SC, USA.
Junmin WhitingDepartment of Biostatistics and Bioinformatics, Moffitt Cancer Center, Tampa, FL, USA.
Mariana ArevaloDepartment of Health Outcomes and Behavior, Moffitt Cancer Center, Tampa, FL, USA.
Monica L KastingDepartment of Public Health, College of Health and Human Sciences, Purdue University, West Lafayette, IN, USA.
Susan T VadaparampilDepartment of Health Outcomes and Behavior, Moffitt Cancer Center, Tampa, FL, USA; Department of Oncologic Sciences, Morsani College of Medicine, University of South Florida, Tampa, FL, USA; Center for Immunization and Infection Research in Cancer, Moffitt Cancer Center, Tampa, FL, USA.
Katharine J HeadDepartment of Communication Studies, Indiana University-Indianapolis, Indianapolis, IN, USA.
Shannon M ChristyDepartment of Health Outcomes and Behavior, Moffitt Cancer Center, Tampa, FL, USA; Department of Oncologic Sciences, Morsani College of Medicine, University of South Florida, Tampa, FL, USA; Center for Immunization and Infection Research in Cancer, Moffitt Cancer Center, Tampa, FL, USA. Electronic address: Shannon.Christy@Moffitt.org.

Funding

TRANSLATIONAL RESEARCHP30CA076292 · NCI · UNIVERSITY OF SOUTH FLORIDA · PI KENNETH Lynn WRIGHT · 1998 to 2026
$93.5M
South Carolina Clinical & Translational Research Institute (SCTR)UL1TR001450 · NCATS · MEDICAL UNIVERSITY OF SOUTH CAROLINA · PI BRADY, KATHLEEN T., FLUME, PATRICK A · 2015 to 2024
$41.1M
The South Carolina Clinical & Translational Research Institute (SCTR)UM1TR005294 · NCATS · MEDICAL UNIVERSITY OF SOUTH CAROLINA · PI KATHLEEN T. BRADY, PATRICK A FLUME · 2025 to 2026
$7.6M
Behavioral Oncology Education & Career DevelopmentT32CA090314 · NCI · H. LEE MOFFITT CANCER CTR & RES INST · PI Vani N Simmons, SUSAN T VADAPARAMPIL · 2019 to 2026
$2.9M
NCATS NIH HHS UL1 TR001450NCATS NIH HHS UM1 TR005294NCI NIH HHS P30 CA076292NCI NIH HHS T32 CA090314
6 · The paper itself

Abstract

objectiveHuman papillomavirus (HPV) vaccine is approved for those aged 9-45 years. However, HPV vaccine uptake remains suboptimal in the United States (U.S.), particularly among young and mid-age adults. This paper describes HPV vaccine patient-clinician communication, clinician recommendation receipt, and HPV vaccine uptake among U.S. adults who were eligible for the HPV vaccine as adults.

methodsU.S. adults up to age 45 and who were aged 18+ when the HPV vaccine was approved were recruited for an online survey (n = 1107) between February-March 2021. Multivariable logistic regression analyses were used to assess: (1) clinician-patient HPV vaccination discussions; (2) ever having received an HPV vaccine recommendation from a clinician; and (3) HPV vaccine uptake.

resultsThirty-four percent of participants reported having prior HPV vaccine discussions with a clinician, 31.1 % reporting ever having received a clinician recommendation for the vaccine, and only 23.8 % reported receiving the vaccine. Receiving the HPV vaccine was positively associated with prior HPV vaccine discussions (aOR: 2.93; 95 % CI: 1.98-4.35) and ever receiving an HPV vaccine recommendation from a clinician (aOR: 10.64; 95 % CI: 7.14-15.88). Additional factors consistently associated with all three models (discussing, receiving a clinician recommendation, and vaccine uptake) include higher HPV vaccine knowledge and higher HPV vaccine embarrassment.

conclusionsUnvaccinated age-eligible adults represent a missed opportunity for HPV-related cancer prevention. Interventions to support clinicians providing care to young and mid-age adults are needed to increase clinician discussions and recommendations of the HPV vaccine and patient uptake of the HPV vaccine.

Indexed as

CommunicationPapillomavirus InfectionsPapillomavirus VaccinesPatient Acceptance of Health CarePhysician-Patient RelationsVaccinationAdolescentAdultFemaleHealth Knowledge, Attitudes, PracticeHuman Papillomavirus VirusesHumansMaleMiddle AgedSurveys and QuestionnairesUnited StatesPapillomavirus VaccinesClinician recommendationHPV vaccinationHPV vaccine uptakeHuman papillomavirusMid-age adultsPatient-clinician discussion

Identifiers

PMID40188881
PMCPMC12068963

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.