Evidence map›Paper›PMID 40188701›Full record

ArticleGait & posture2025

Age-related trajectories of muscle strength and power in individuals with cerebral palsy and the relationship to walking capacity.

Mattie E Pontiff, Noelle G Moreau

Abstract read
In one paragraph

Article in Gait & posture, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

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2 · The registry

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3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

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4 · The record

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PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors.

Mattie E PontiffUniversity of Colorado Anschutz Medical Campus and Rocky Mountain Regional VAMC, Aurora, CO, United States.
Noelle G MoreauDepartment of Physical Therapy, LSUHSC, New Orleans, 1900 Gravier St., 7th Floor, New Orleans, LA 70112, United States. Electronic address: nmorea@lsuhsc.edu.

Funding

Power Training Combined with Interval Treadmill Training to Improve Walking Activity in Cerebral PalsyR01HD091089 · NICHD · LSU HEALTH SCIENCES CENTER · PI MOREAU, NOELLE G · 2018 to 2022
$2.5M
NICHD NIH HHS R01 HD091089
6 · The paper itself

Abstract

backgroundCessation of walking is a consequence of aging in many individuals with Cerebral Palsy (CP). Muscle strength and power are associated with walking capacity in those with CP. However, the age-related trajectories in strength and power and how they compare to trajectories of those with typical development (TD) are unknown. Additionally, determining which measure of muscle performance (strength or power) is more closely associated with walk capacity may guide clinical assessments of muscle performance that are most meaningful to mobility in those with CP. RESEARCH QUESTION: Do the associations between age and muscle performance differ between individuals with CP and TD? Is muscle power more strongly associated with walking capacity compared to muscle strength in those with CP?

methodsAge-related differences in muscle strength and power between individuals with CP (n = 66, 13.5 ± 4.8 years, GMFCS I-IV) and TD (n = 42, 16.8 ± 6.1 years) were examined with linear regression and ANCOVA. Associations between measures of walking capacity and strength and power were evaluated with Pearson's (r).

resultsLinear regression between muscle strength and power with age was statistically significant in both groups. Age-related changes in strength and power were significantly greater in TD compared to CP. Linear regression between normalized strength and power with age was significant in those with TD but not in CP. All measures of walking capacity were significantly associated with both strength and power, but muscle power was more strongly correlated (p < 0.05). SIGNIFICANCE: Although age-related changes were observed in both groups, individuals with TD demonstrated greater age-related changes in muscle power and strength than those with CP. After normalizing by body mass, no age-related changes were observed in CP, suggesting that gains in power and strength are insufficient to offset increases in body mass with age. Muscle power had a stronger relationship to walking capacity than strength.

Indexed as

AgingCerebral PalsyMuscle StrengthWalkingAdolescentAdultAge FactorsChildFemaleHumansLinear ModelsMaleMuscle, SkeletalYoung AdultCerebral PalsyGait speedGait velocityMuscle powerMuscle strength

Identifiers

PMID40188701
PMCPMC12636272

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.